The Hinton lab aims to elucidate the molecular mechanisms that regulate molecule transfer and morphology changes between the mitochondria and the endoplasmic reticulum and how these mechanisms are altered during pathophysiological states, particularly diabetes, obesity, and cardiovascular disease.
Title: Graduate Student
Graduate student is a yearly contract determined on the basis of length of program and satisfactory progress being made throughout the program.
No requirements beyond a B.S. or B.A. in a field relevant to this lab. The ideal candidate will demonstrate a commitment to excellence in research, diversity in STEMM fields, and interest in the topics relevant to the Hinton lab.
Additional Qualifications (Optional):
- Expertise in Patch Clamping
- Expertise in Surgery (e.g. OVX, Telemetry (Blood Pressure) Surgery, and ICV cannulation)
- Expertise in making primary cells
- Expertise in cell culture and primary cell culture
- Experience in animal studies.
- Experience working with Drosophila
- Expertise in Transmission Electron Microscopy
- Expertise in Serial Block Facing Microscopy or Focus Ion Bean Microscopy
- TEM analysis
Training for Applicant:
We will learn various techniques that may include primary cell isolation, bioinformatics programming for large data sets, in vitro exercise, confocal/STED microscopy, TEM analysis, 3D EM microscopy techniques, and various forms of image analysis. Additionally, we will utilize primary and human cell lines, mouse, and fly model organisms to delineate pathophysiological states.
Cultural Competency and Mentoring for Applicant:
The Hinton lab seeks an student that is committed to being mentored using innovative mentoring tools, such as self-assessment tools (e.g. implicit bias training, personality test, learning styles, and love language test), mentoring maps, individual development training plan, career development activities, and cultural competence training. Additionally, the Hinton lab seeks applicants with enthusiasm for working with a diverse student population. Importantly, the Hinton lab is made up a diverse group of individuals and the Hinton lab strongly encourages applications from candidates with a record of experience or demonstrated a commitment to working with all backgrounds, including but not limited to: racial and ethnic minorities, women, individuals who identify with LGBTQ+ communities, individuals with disabilities, individuals from lower income backgrounds, and/or first generation college graduates.
To apply email: email@example.com. I will need the following documents to be considered for this position.
- A current CV/Resume
- A current transcript
- Contact info for 3 references for letters of recommendations
- 1-page Personal Statement Page detailing your goals
- 1-page Research statement Page detailing your past research experiences
Prior to Beginning:
For all potential students, an applicant must first do rotations and submit an independent development plan to the PI. This is to ensure that their goals align with the goals of the Hinton lab and to confirm that the applicant will be a good fit for the lab.
Description and Responsibilities:
The successful applicant will be working on project(s) (e.g. a biophysics project focused on mitochondrial networks using 3D Microscopy, a biochemical and cell biology-based project that focuses on the MICOS complex or TMEm135, and a physiology project that explores insulin resistance, MERCs, and mitochondrial dynamics) in conjunction with the staff scientist, post-doctoral researchers, PI, and other lab members to successfully carry out research. The applicant will have the opportunity to work across their department, along with the broader academic community, to accomplish their research goals. Research will be multi-faceted and may include training, to name a few, in imaging, tissue isolation, and cell culture. In addition to this, the candidate will work on professional development. This includes writing primary manuscripts or literature reviews and engaging in the relevant opportunities and experiences that are required for the candidate to successfully transition to the next stage in their scientific career (e.g. Attend Diabetes Center Seminar series, Discovery Sciences Emerging Scholars lectures Discovery series, Metabolism Interests Group, and all other designated seminars and conferences).