Light-induced isomerization of apoptolidin a leads to inversion of C2-C3 double bond geometry.
Authors
Bachmann
BO
Brian O
,
McNees
R
Ruth
,
Melancon
BJ
Bruce J
,
Ghidu
VP
Victor P
,
Clark
R
Rachel
,
Crews
BC
Brenda C
,
Deguire
SM
Sean M
,
Marnett
LJ
Lawrence J
,
Sulikowski
GA
Gary A
.
Organic letters. 2010 7 2; 12(13).
2944-7
Organic letters. 2010 7 2; 12(13).
2944-7
Abstract
The isolation, characterization, and cytotoxicity against H292 cells of apoptolidin G are reported. Apoptolidin G is shown to be derived by a light-induced isomerization of the C2-C3 carbon-carbon double bond of apoptolidin A.
The isolation, characterization, and cytotoxicity against H292 cells of apoptolidin G are reported. Apoptolidin G is shown to be derived by a light-induced isomerization of the C2-C3 carbon-carbon double bond of apoptolidin A.