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Neuronal Fat and Dendrite Morphogenesis: The Goldilocks Effect


Sundararajan LLakshmi , Miller DMDavid M . Trends in Neurosciences. 2018 3 13; 41(5). 250-252


Two recent studies by Meltzer et al. and Ziegler et al. use Drosophila larvae to demonstrate that cell-autonomous regulation of lipid biosynthesis defines the complexity and function of highly branched nociceptive neurons. Their findings show that lipid biosynthesis in the neuron is fine-tuned for optimal dendrite morphology and sensitivity.