Neuronal Fat and Dendrite Morphogenesis: The Goldilocks Effect
AUTHORS
Sundararajan
LLakshmi ,
Miller
DMDavid M .
Trends in Neurosciences. 2018 3 13; 41(5).
250-252
- PMID: 29548516[PubMed].
- PMCID: PMC5924613.
ABSTRACT
Two recent studies by Meltzer et al. and Ziegler et al. use Drosophila larvae to demonstrate that cell-autonomous regulation of lipid biosynthesis defines the complexity and function of highly branched nociceptive neurons. Their findings show that lipid biosynthesis in the neuron is fine-tuned for optimal dendrite morphology and sensitivity.