The Gould laboratory conducts foundational research on the molecular basis of cell division, a highly conserved process central to development and tissue maintenance. Eukaryotic cells accomplish cell division with exquisite spatial and temporal control. A key event during cell division is the formation of an actin- and myosin-based cytokinetic ring that constricts to physically separate two new daughter cells. Our lab is fascinated by the question of how the cytokinetic ring is assembled and organized on the plasma membrane. We are also interested in how the assembly and constriction of the cytokinetic ring is coordinated with chromosne segregation to ensure genomic integrity. We have made fundamental, pioneering discoveries in the mechanisms that control cell division using a multi-disciplinary approach that includes super-resolution microscopy, mass spectrometry-based proteomics, genetics, structural biology, biochemisty, and biochemical reconstitution.
For more updates on the Gould Lab, follow us on Twitter @Gould_Lab.
We are members of the Department of Cell and Developmental Biology at Vanderbilt University in Nashville, TN. For more information about our institution and life in Nashville, visit our links or Contact Us.
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