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Research

 

Combining 3View serial block face scanning electron microscopy and imaging software, we generate 3D images of secretory cell types, like tuft cells, to understand their subcellular structures and their interactions with stromal cells and other epithelial cells.

Video-1

These techniques have allowed us to discover previously un-described subcellular organelles in neoplastic tuft cells, including nucleus-associated lipid droplets.

Video-2