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Recommendations

General Recommendations

1H (typical samples) Any spectrometer
1H (very dilute samples) 600 MHz [Marlin]
13C NMR The 600 MHz [Marlin] cryoprobe is ca. 4x more sensitive than all others
31P,29Si,11B NMR etc 400 MHz [Snook], 400 MHz [Perch], 400 MHz [MRBIV] or 500 MHz [Biomol]
19F NMR 400 MHz [Snook], 400 MHz [Perch], 400 MHz [MRBIV] or 500 MHz [Biomol]
(Note: 19F is slightly less sensitive on 400 MHz [Perch])

Summary of Capabilities by Spectrometer

  • 400 MHz [Snook]
    Current Probe 5 mm broadband TBO probe (H,P,X)
    Best High abundance heteronuclei (31P, 19F, 29Si, 11B)
    Routine 1H experiments, 1H-detected 2-dimensional experiments (e.g. COSY, HMBC etc)
    Acceptable X-channel nuclei (13C, 31P, etc)
  • 400 MHz [Perch]
    Current Probe 5 mm broadband 3-channel TBO probe (H,F,X)
    Unique Double decoupling experiments with 19F (e.g. 13C with 1H and 19F decoupling)
    Best High abundance heteronuclei (31P, 29Si, 11B)
    Routine 1H experiments, 1H-detected 2-dimensional experiments (e.g. COSY, HMBC etc)
    Acceptable 19F experiments, X-channel nuclei (13C, 31P, etc)
  • 600 MHz [Marlin]
    Current Probe 5 mm TCI (inverse) cryoprobe
    Best 1-dimensional 1H and 1H-detected 2-dimensional experiments (e.g. COSY, HMBC etc)
    Excellent 13C
    Not Possible All nuclei other than 1H, 13C or 15N
  • 400 MHz [MRBIV]
    Current Probe 5 mm broadband (BBFO) probe
    Best High abundance heteronuclei (31P, 19F, 29Si, 11B)
    Acceptable 1H experiments, H-detected 2-dimensional experiments (e.g. COSY, HMBC etc), 13C NMR
  • 500 MHz [Biomolec]
    Current Probe 5 mm broadband (BBFO) probe
    Best High abundance heteronuclei (31P, 19F, 29Si, 11B)
    Acceptable 1H experiments, H-detected 2-dimensional experiments (e.g. COSY, HMBC etc), 13C NMR
    Additional Can be used with tall NMR tubes