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Ren Lab Publications

2021

Zhang K , , , Garcia-Sastre A , Ren Y , Wozniak RW , Fontoura BMA , Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression Science Advances. 2021 Feb 5; 7 (6).
Xie Y , Clarke BP , Kim Y , Ivey AL , Hill PS , Shi Y , Ren Y , Cryo-EM structure of the yeast TREX complex and coordination with the SR-like protein Gbp2 eLife. 2021 Mar 31; 10
Xie Y , Lord CL , Clarke BP , Ivey AL , Hill PS , McDonald WH , Wente SR , Ren Y , Structure and activation mechanism of the yeast RNA Pol II CTD kinase CTDK-1 complex Proceedings of the National Academy of Sciences of U.S.A. . 2021 Jan 19;

2020

Dollins DE , Xiong J , Endo-Streeter S , Anderson D , Bansal V , Ponder J , Ren Y , York JD , A Structural Basis for Lithium and Substrate Binding of an Inositide Phosphatase Journal of Biological Chemistry. 2020 Nov 10;
Miorin L , Kehrer T , Sanchez-Aparicio M , Zhang K , Cohen P , Patel R , Cupic A , Makio T , Mei M , , , , , , , Wozniak R , Ren Y , Rosenberg B , Fontoura BM , Garcia-Sastre A , SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling Proceedings of the National Academy of Sciences of U.S.A.. 2020 Oct 23;
Morris A , Wang Z , Ivey AL , Xie Y , Hill PS , Schey K , Ren Y , Cellular mRNA export factor UAP56 recognizes nucleic acid binding site of influenza virus NP protein. Biochemical and Biophysical Research Communications. 2020 Feb 19;

2019

Xie Y , Ren Y , Mechanisms of nuclear mRNA export: A structural perspective Traffic. 2019 Sep 12; 11 (20). 829-840
Zhang K , Xie Y , Muñoz-Moreno R , Wang J , Zhang L , Esparza M , García-Sastre A , Fontoura BM , Ren Y , Structural basis for influenza virus NS1 protein block of mRNA nuclear export Nature Microbiology . 2019 Jul 1;

2018

Ren Y , Wente SR , Günter Blobel (1936–2018) Developmental Cell. 2018 ; 2 (45). p151-152

2017

2014

Quan B , Seo HS , Blobel G , Ren Y , Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1 • Nup98). Proceedings of the National Academy of Sciences of the United States of America. 2014 Jun 24; 111 (25). 9127-32

2013

Xu Kai , Rockx Barry , Xie Yihu , DeBuysscher Blair , Fusco Deborah , Zhu Zhongyu , Chan Yee-Peng , Xu Yan , Luu Truong , Cer Regina , Feldmann Heinz , Mokashi Vishwesh , Dimitrov Dimiter , Bishop-Lilly Kimberly , Broder Christopher , Nikolov Dimitar , Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody PLoS Pathogens. 2013 ; 10 (9).

2010

Takai Kiroyuki , Xie Yihu , de Lange Titia , Pavletich Nikola , Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes. Genes & Development. 2010 ; 18 (24).
Ren Y , Seo HS , Blobel G , Hoelz A , Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1. Proceedings of the National Academy of Sciences of the United States of America. 2010 Jun 8; 107 (23). 10406-11
Ren Q , Wimmer C , Chicka MC , Ye S , Ren Y , Hughson FM , Whiteheart SW , Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis. Blood. 2010 Aug 12; 116 (6). 869-77

2009

Ren Y , Yip CK , Tripathi A , Huie D , Jeffrey PD , Walz T , Hughson FM , A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1. Cell. 2009 Dec 11; 139 (6). 1119-29
Tripathi A , Ren Y , Jeffrey PD , Hughson FM , Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex. Nature structural & molecular biology. 2009 Feb ; 16 (2). 114-23

2004

Ren Y , Wang WH , Wang YH , Case M , Qian W , McLendon G , Huang ZX , Mapping the electron transfer interface between cytochrome b5 and cytochrome c. Biochemistry. 2004 Mar 30; 43 (12). 3527-36

2001

Wang YH , Ren Y , Wang WH , Xie Y , Huang ZX , The regulation of surface charged residues on the properties of cytochrome b5. Journal of protein chemistry. 2001 Aug ; 20 (6). 487-93