SARS-CoV-2 shares a similar character with influenza. Check out our collaborative work on Nsp1 published in Science Advances!
Feb. 5, 2021
Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression
https://advances.sciencemag.org/content/7/6/eabe7386
Congratulations Mei for his findings published in PNAS! A wonderful collaborative work on elucidating how SARS-CoV-2 hijacks Nup98 to antagonize interferon signaling!
Oct. 24, 2020
We previously revealed the mechanism of how vesicular stomatitis virus hijacks Nup98 to block host gene expression. Our most recent work published in PNAS shows that SARS-CoV-2 utilizes a similar strategy to target Nup98 in order to block interferon signaling.
