Ren Lab Publications
2024
Zhang
,
Cagatay
T ,
Xie
D ,
Angelos
AE ,
Cornelius
S ,
Aksenova
V ,
Aslam
S ,
He
Z ,
Esparza
M ,
Vazhavilla
A ,
Dasso
M ,
Garcia-Sastre
A ,
Ren
Y ,
Fontoura
BMA ,
Cellular NS1-BP Protein Interacts with the mRNA Export Receptor NXF1 to Mediate Nuclear Export of Influenza Virus M mRNAs
Journal of Biological Chemistry.
2024 Oct
;
Clarke
BP ,
Angelos
AE ,
Mei
M ,
Hill
PS ,
Xie
Y ,
Ren
Y ,
Cryo-EM structure of the CBC-ALYREF complex
eLife.
2024 Sep
16;
- PMID: 39282949 [PubMed].
Mei
M ,
Cupic
A ,
Miorin
L ,
Ye
C ,
Cagatay
T ,
Zhang
K ,
Patel
K ,
Wilson
N ,
McDonald
WH ,
Crossland
N ,
Lo
M ,
Rutkowska
M ,
Aslam
S ,
Mena
I ,
Martinez-Sobrido
L ,
Ren
Y ,
Garcia-Sastre
A ,
Fontoura
BMA ,
Inhibition of mRNA nuclear export promotes SARS-CoV-2 pathogenesis
PNAS.
2024 May
20;
(121(22)).
2023
Clarke
BP ,
Angelos
AE ,
Mei
M ,
Hill
PS ,
Xie
Y ,
Ren
Y ,
Cryo-EM structure of the CBC-ALYREF complex
bioRxiv.
2023 Oct
26;
(https://www.biorxiv.org/content/10.1101/2023.10.01.559959v1).
Xie
Yihu ,
Gao
Shengyan ,
Zhang
Ke ,
Bhat
Prasanna ,
Clarke
Bradley ,
Batten
Kimberly ,
Mei
Menghan ,
Gazzara
Matthew ,
Shay
Jerry ,
Lynch
Kristen ,
Angelos
Alexia ,
Hill
Pate ,
Ivey
Austin ,
Fontoura
Beatriz ,
Ren
Yi ,
Structural basis for high-order complex of SARNP and DDX39B to facilitate mRNP assembly
Cell Reports.
2023
;
42
(8).
- PMID: 37578863 [PubMed].
2021
Zhang
K ,
,
,
Garcia-Sastre
A ,
Ren
Y ,
Wozniak
RW ,
Fontoura
BMA ,
Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression
Science Advances.
2021 Feb
5;
7
(6).
- PMID: 33547084 [PubMed].
Xie
Y ,
Clarke
BP ,
Kim
Y ,
Ivey
AL ,
Hill
PS ,
Shi
Y ,
Ren
Y ,
Cryo-EM structure of the yeast TREX complex and coordination with the SR-like protein Gbp2
eLife.
2021 Mar
31;
10
- PMID: 33787496 [PubMed].
Xie
Y ,
Lord
CL ,
Clarke
BP ,
Ivey
AL ,
Hill
PS ,
McDonald
WH ,
Wente
SR ,
Ren
Y ,
Structure and activation mechanism of the yeast RNA Pol II CTD kinase CTDK-1 complex
Proceedings of the National Academy of Sciences of U.S.A. .
2021 Jan
19;
- PMID: 33431688 [PubMed].
2020
Dollins
DE ,
Xiong
J ,
Endo-Streeter
S ,
Anderson
D ,
Bansal
V ,
Ponder
J ,
Ren
Y ,
York
JD ,
A Structural Basis for Lithium and Substrate Binding of an Inositide Phosphatase
Journal of Biological Chemistry.
2020 Nov
10;
- PMID: 33172890 [PubMed].
Miorin
L ,
Kehrer
T ,
Sanchez-Aparicio
M ,
Zhang
K ,
Cohen
P ,
Patel
R ,
Cupic
A ,
Makio
T ,
Mei
M ,
,
,
,
,
,
,
Wozniak
R ,
Ren
Y ,
Rosenberg
B ,
Fontoura
BM ,
Garcia-Sastre
A ,
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
Proceedings of the National Academy of Sciences of U.S.A..
2020 Oct
23;
- PMID: 33097660 [PubMed].
Morris
A ,
Wang
Z ,
Ivey
AL ,
Xie
Y ,
Hill
PS ,
Schey
K ,
Ren
Y ,
Cellular mRNA export factor UAP56 recognizes nucleic acid binding site of influenza virus NP protein.
Biochemical and Biophysical Research Communications.
2020 Feb
19;
- PMID: 32085897 [PubMed].
2019
Xie
Y ,
Ren
Y ,
Mechanisms of nuclear mRNA export: A structural perspective
Traffic.
2019 Sep
12;
11
(20).
829-840
- PMID: 31513326 [PubMed].
Zhang
K ,
Xie
Y ,
Muñoz-Moreno
R ,
Wang
J ,
Zhang
L ,
Esparza
M ,
García-Sastre
A ,
Fontoura
BM ,
Ren
Y ,
Structural basis for influenza virus NS1 protein block of mRNA nuclear export
Nature Microbiology .
2019 Jul
1;
- PMID: 31263181 [PubMed].
2018
Ren
Y ,
Wente
SR ,
Günter Blobel (1936–2018)
Developmental Cell.
2018
;
2
(45).
p151-152
2017
Ren
Yi ,
Schmiege
Philip ,
Blobel
Günter ,
Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1.
eLife.
2017 Jan
6;
6
- PMID: 28059701 [PubMed].
2014
Quan
B ,
Seo
HS ,
Blobel
G ,
Ren
Y ,
Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1 • Nup98).
Proceedings of the National Academy of Sciences of the United States of America.
2014 Jun
24;
111
(25).
9127-32
- PMID: 24927547 [PubMed].
- PMCID: PMC4078809.
2013
Xu
Kai ,
Rockx
Barry ,
Xie
Yihu ,
DeBuysscher
Blair ,
Fusco
Deborah ,
Zhu
Zhongyu ,
Chan
Yee-Peng ,
Xu
Yan ,
Luu
Truong ,
Cer
Regina ,
Feldmann
Heinz ,
Mokashi
Vishwesh ,
Dimitrov
Dimiter ,
Bishop-Lilly
Kimberly ,
Broder
Christopher ,
Nikolov
Dimitar ,
Crystal structure of the Hendra virus attachment G glycoprotein bound to a potent cross-reactive neutralizing human monoclonal antibody
PLoS Pathogens.
2013
;
10
(9).
- PMCID: PMC3795035.
2010
Takai
Kiroyuki ,
Xie
Yihu ,
de Lange
Titia ,
Pavletich
Nikola ,
Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Genes & Development.
2010
;
18
(24).
- PMCID: PMC2939364.
Ren
Y ,
Seo
HS ,
Blobel
G ,
Hoelz
A ,
Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1.
Proceedings of the National Academy of Sciences of the United States of America.
2010 Jun
8;
107
(23).
10406-11
- PMID: 20498086 [PubMed].
- PMCID: PMC2890840.
Ren
Q ,
Wimmer
C ,
Chicka
MC ,
Ye
S ,
Ren
Y ,
Hughson
FM ,
Whiteheart
SW ,
Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis.
Blood.
2010 Aug
12;
116
(6).
869-77
- PMID: 20435885 [PubMed].
- PMCID: PMC2924225.
2009
Ren
Y ,
Yip
CK ,
Tripathi
A ,
Huie
D ,
Jeffrey
PD ,
Walz
T ,
Hughson
FM ,
A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1.
Cell.
2009 Dec
11;
139
(6).
1119-29
- PMID: 20005805 [PubMed].
- PMCID: PMC2806190.
- NIHMSID: NIHMS165832
Tripathi
A ,
Ren
Y ,
Jeffrey
PD ,
Hughson
FM ,
Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.
Nature structural & molecular biology.
2009 Feb
;
16
(2).
114-23
- PMID: 19151722 [PubMed].
- PMCID: PMC2635920.
- NIHMSID: NIHMS85435
2004
Ren
Y ,
Wang
WH ,
Wang
YH ,
Case
M ,
Qian
W ,
McLendon
G ,
Huang
ZX ,
Mapping the electron transfer interface between cytochrome b5 and cytochrome c.
Biochemistry.
2004 Mar
30;
43
(12).
3527-36
- PMID: 15035623 [PubMed].
2001
Wang
YH ,
Ren
Y ,
Wang
WH ,
Xie
Y ,
Huang
ZX ,
The regulation of surface charged residues on the properties of cytochrome b5.
Journal of protein chemistry.
2001 Aug
;
20
(6).
487-93
- PMID: 11760123 [PubMed].