Author
A review article in the Journal of Cell Science
Feb. 8, 2022—Indrayani published a review in the Journal of Cell Science summarizing glypican-mediated Wnt distribution. In this review, we summarize, critique, and provide revisions to all the reported models of Wnt distribution. We especially focus on glypican-mediated mechanisms, which primarily establish Wnt gradients in vivo. An up-to-date summary of seminal studies on how glypicans spread extracellular Wnts...
Indrayani recieved a K99!
Jan. 9, 2022—Indrayani received a K99 award from the NIGMS to study mechanisms of Wg/Wnt regulation by glypican Dlp (01/22-12/23). The award funds research where she will integrate the Drosophila genetic tools with biochemical, proteomic, and imaging approaches to investigate how Dlp-mediated regulation of Wnt signaling is affected by proteolytic cleavage of Dlp my Matrix Metalloprotease2 (Mmp2) in developmental...
Kimi had a baby!
Jan. 8, 2022—Congratulations to Kimi and Zach as they welcomed Sophie on December 4th, 2021! Everyone is doing well!
A new paper in PLoS One
Jan. 8, 2022—James O’Connor et al published a new paper in PLoS One! This work characterized several different types of cellular damage within a wounded epithelial tissue, allowing for distinct regions of damage to be estimated after measuring any one type of damage.