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A review article in the Journal of Cell Science

Posted by on Tuesday, February 8, 2022 in Lab News.

Indrayani published a review in the Journal of Cell Science summarizing glypican-mediated Wnt distribution. In this review, we summarize, critique, and provide revisions to all the reported models of Wnt distribution. We especially focus on glypican-mediated mechanisms, which primarily establish Wnt gradients in vivo. An up-to-date summary of seminal studies on how glypicans spread extracellular Wnts was lacking and the publication of this article was timely.