Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)
AUTHORS
Jain
SSanjay ,
Pei
LLiming ,
Spraggins
JMJeffrey M ,
Angelo
MMichael ,
Carson
JPJames P ,
Gehlenborg
NNils ,
Ginty
FFiona ,
Gonçalves
JPJoana P ,
Hagood
JSJames S ,
Hickey
JWJohn W ,
Kelleher
NLNeil L ,
Laurent
LCLouise C ,
Lin
SShin ,
Lin
YYiing ,
Liu
HHuiping ,
Naba
AAlexandra ,
Nakayasu
ESErnesto S ,
Qian
WJWei-Jun ,
Radtke
AAndrea ,
Robson
PPaul ,
Stockwell
BRBrent R ,
Van de Plas
RRaf ,
Vlachos
ISIoannis S ,
Zhou
MMowei ,
,
Börner
KKaty ,
Snyder
MPMichael P .
Nature cell biology. 2023 7 19; 25(8).
1089-1100
- PMID: 37468756[PubMed].
ABSTRACT
The Human BioMolecular Atlas Program (HuBMAP) aims to create a multi-scale spatial atlas of the healthy human body at single-cell resolution by applying advanced technologies and disseminating resources to the community. As the HuBMAP moves past its first phase, creating ontologies, protocols and pipelines, this Perspective introduces the production phase: the generation of reference spatial maps of functional tissue units across many organs from diverse populations and the creation of mapping tools and infrastructure to advance biomedical research.