MALDI Imaging Mass Spectrometry Spatially Maps Age-Related Deamidation and Truncation of Human Lens Aquaporin-0.
AUTHORS
Wenke| Rose| Spraggins| Schey
JL| KL| JM| KLJamie L| Kristie L| Jeffrey M| Kevin L .
Investigative ophthalmology & visual science. 2015 11 ; 56(12).
7398-405
- PMID: 26574799[PubMed].
- PMCID: PMC4675204.
ABSTRACT
To spatially map human lens Aquaporin-0 (AQP0) protein modifications, including lipidation, truncation, and deamidation, from birth through middle age using matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry (IMS).
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