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The enteropathy of prostaglandin deficiency.


AUTHORS

Adler DHDavid H , Phillips JA John A , Cogan JD Joy D , Iverson TM Tina M , Schnetz-Boutaud N Nathalie , Stein JA Jeffrey A , Brenner DA David A , Milne GL Ginger L , Morrow JD Jason D , Boutaud O Oliver , Oates JA John A . Journal of gastroenterology. 2009 ; 44 Suppl 19(). 1-7

ABSTRACT

Small intestinal ulcers are frequent complications of therapy with nonsteroidal anti-inflammatory drugs (NSAIDs). We present here a genetic deficiency of eicosanoid biosynthesis that illuminates the mechanism of NSAID-induced ulcers of the small intestine.


Small intestinal ulcers are frequent complications of therapy with nonsteroidal anti-inflammatory drugs (NSAIDs). We present here a genetic deficiency of eicosanoid biosynthesis that illuminates the mechanism of NSAID-induced ulcers of the small intestine.