Select Publications:
Pinette J.A., Myers J.W., Park W.Y., Bryant H.G., Wilson G.A., Vue Z., Nunn E.R., Cottam M.A., Hinton A.O., Spinelli J.B., Cartailler J-P., and Zaganjor E. Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis. J Lipid Res. 2024 Sep 6:100641. PMID: 39245323
Shinde A.B.*, Nunn E.R.*, Wilson G.A., Chvasta M.T., Pinette J.A., Myers J.W., Peck S.H., Spinelli, J.B., and Zaganjor E. (2023) Inhibition of nucleotide biosynthesis disrupts lipid accumulation and adipogenesis. J Biol Chem. 2023:104635.
Zaganjor E#, Yoon, H., Spinelli J.B., Nunn E.R., Laurent, G., Keskinidis, P., Sivaloganathan, S., Joshi, S., Notarangelo, G, Mulei, S., Chvasta M.T., Tucker S.A., Kalafut, K., Van de Ven, R., Clish, C.B., and Haigis, M.C#. (2021) SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis. Cell Reports 36(2) 109345.
Gonzalez Herrera KN*, Zaganjor E*, Ishikawa Y, Spinelli JB, Yoon H, Lin JR, et al. Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3. Cell reports. 2018;22(8):1945-55. doi: 10.1016/j.celrep.2018.01.076. PubMed PMID: 29466723.
Lee JJ*, van de Ven RAH*, Zaganjor E*, Ng MR, Barakat A, Demmers J, et al. Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3. Proceedings of the National Academy of Sciences of the United States of America. 2018;115(27):7057-62. doi: 10.1073/pnas.1800440115. PubMed PMID: 29915029.
Zaganjor E, Weil LM, Gonzales JX, Minna JD, Cobb MH. Ras transformation uncouples the kinesin-coordinated cellular nutrient response. Proceedings of the National Academy of Sciences of the United States of America. 2014;111(29):10568-73. doi: 10.1073/pnas.1411016111. PubMed PMID: 25002494.
Zaganjor E, Osborne JK, Weil LM, Diaz-Martinez LA, Gonzales JX, Singel SM, et al. Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells. Oncogene. 2014;33(47):5457-66. doi: 10.1038/onc.2013.486. PubMed PMID: 24240690.
Yagoda N*, von Rechenberg M*, Zaganjor E*, Bauer AJ, Yang WS, Fridman DJ, et al. RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature. 2007;447(7146):864-8. doi: 10.1038/nature05859. PubMed PMID: 17568748.
Complete list of publications: https://pubmed.ncbi.nlm.nih.gov/?term=zaganjor+e&sort=date