Targeted Lipidomics

Lipids are important to many biological processes in the aging and especially are critical for Alzheimer’s disease. We are beginning to understand the role of lipid metabolism in Alzheimer’s disease using untargeted and targeted lipidomics workflows. These methods are based on mass spectrometry and can be used to study many different lipid classes simultaneously from biological fluids such as human plasma. Projects in the lab are centered on development of robust workflows to study targeted lipids in disease.