Publications
2023
More is different: Reconstituting complexity in microtubule regulation
J Biol Chem. 2023 Dec; 299(12):105398
PMID: 3789404 doi: 10.1016/j.jbc.2023.105398
CLASPs stabilize the pre-catastrophe intermediate state between microtubule growth and shrinkage
J Cell Biol. 2023 Jul 3;222(7):e202107027
PMID: 37184584 doi: 10.1083/jcb.202107027
CLASP2 facilitates dynamic actin filament organization along the mircrotubule lattice
N. C. Rodgers, Elizabeth J. Lawrence, A. V. Sawant, N. Efimova, G. Gonzalez-Vasquez, T. T. Hickman, I. Kaverina, and Marija Zanic
Molecular Biology of the Cell. 2023; 34(3):br3
PMCID: PMC10011731 doi: 10.1091/mbc.E22-05-0149
2022
Beyond the GTP-cap: Elucidating the molecular mechanisms of microtubule catastrophe
Veronica J. Farmer, Marija Zanic
Bioessays. 2023 Jan; 45(1): e2200081
PMID: 36398561 doi: 10.1002/bies.202200081
Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli
Cell Reports. 2022 Apr 19; 39(3):110692
PMID: 35443169 doi: 10.1016/j.celrep.2022.110692
Quantification of microtubule stutters: dynamic instability behaviors that are strongly associated with catastrophe
Molecular Biology of the Cell. 2022 March 1; 33(3):ar22
PMID: 35108073 doi: 10.1091/mbc.E20-06-0348
2021
SSNA1 stabilizes dynamic microtubules and detects microtubule damage
Elife. 2021 Dec 31; 10:e67282
PMID: 34970964 doi: 10.7554/eLife.67282
Microtubules regulate pancretic B-cell heterogeneity via spatiotemporal control of insulin secretion hot spots
Elife. 2021 Nov 16; 10:e59912
PMID: 34783306 doi: 10.7554/eLife.59912
XMAP215 promotes microtubule catastrophe by disrupting the growing microtubule end
Veronica J. Farmer, Göker Arpağ, Sarah L. HallMarija Zanic
Journal of Cell Biology. 2021 Feb 20; (10): e202012144
PMID: 34324632 doi: 10.1083/jcb.202012144
TOG-domain proteins
Current Biology. 2021 May 24; 31(10):R499-R501
PMID: 34033778 doi: 10.1016/j.cub.2021.01.039
Impact of the ‘tubulin economy’on the formation and function of the microtubule cytoskeleton
Current Opinion in Cell Biology. 2021 Feb; 68:81-89
PMID: 33160109 doi: 10.1016/j.ceb.2020.09.005
2020
Collective effects of XMAP215, EB1, CLASP2, and MCAK lead to robust microtubule treadmilling
Proc Natl Acad Sci. 2020 Jun 9; 117(23):12847-12855.
PMID:32457163 doi: 10.1073/pnas.2003191117
CLASPs at a glance
Journal of Cell Science. 2020 Apr 24; 133(8):jcs243097
PMID: 32332092 doi: 10.1242/jcs.243097
2019
Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends
Elife. 2019 Sep 3:8:e48117
PMID: 31478831 doi: 10.7554/eLife.48117
Microtubule minus-end stability is dictated by the tubulin off-rate
Journal of Cell Biology. 2019 Sep 2; 218(9):2841-2853
PMID: 31420452 doi: 10.1083/jcb.201905019
Resistance is futile: Centering forces yield for asymmetric cell division
Journal of Cell Biology. 2019 Mar 4; 218(3):727-728
PMID: 30770435 doi: 10.1083/jcb.201902039
Rescuing microtubules from the brink of catastrophe: CLASPs lead the way
Current Opinions in Cell Biology. 2019 Feb:56:94-101
PMID: 30453184 doi: 10.1016/j.ceb.2018.10.011
2018
Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters
Nat Commun. 2018 Jul 9; 9(1):2659
PMID: 29985404 doi: 10.1038/s41467-018-04991-2
Human CLASP2 specifically regulates microtubule catastrophe and rescue
Mol Biol Cell. 2018 May 15;29(10):1168-1177
PMID: 29540526 doi: 10.1091/mbc.E18-01-0016
2017
Phosphoinositide-mediated ring anchoring resists perpendicular forces to promote medial cytokinesis
J Cell Biol. 2017 Oct 2; 216(10):3041-3050
PMID: 28784611 doi: 10.1083/jcb.201705070
2016
Measuring the Effects of Microtubule-Associated Proteins on Microtubule Dynamics In Vitro
Marija Zanic
Methods Mol Biol. 2016:1413:47-61
PMID: 27193842 doi: 10.1007/978-1-4939-3542-0_4
Ahead of the Curve: New Insights into Microtubule Dynamics
F1000Res. 2016 Mar 10:5:F1000 Faculty Rev-314.
PMID: 26998244 doi: 10.12688/f1000research.7439.1
2015
Encoding the microtubule structure: Allosteric interactions between the microtubule +TIP complex master regulators and TOG-domain proteins
Cell Cycle. 2015; 14(9):1375-8
PMID: 25895033 doi: 10.1080/15384101.2015.1026521
2013
Microtubule catastrophe and rescue
Curr Opin Cell Biol. 2013 Feb; 25(1):14-22
PMID: 23092753 doi: 10.1016/j.ceb.2012.09.006
Microtubule dynamic instability: a new model with coupled GTP hydrolysis and multistep catastrophe
Bioessays. 2013 May; 35(5):452-61
PMID: 23532586 doi: 10.1002/bies.201200131
Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels
Nat Cell Biol. 2013 Jun; 15(6):688-93
PMID: 23666085 doi: 10.1038/ncb2744
2012
Islands containing slowly hydrolyzable GTP analogs promote microtubule rescues
PLos One. 2012; 7(1):e30103
PMID: 22272281 doi: 10.1371/journal.pone.0030103
2011
XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region
Proc Natl Acad Sci U.S.A. 2011 Feb 15; 108(7):2741-6
PMID: 21282620 doi: 10.1073/pnas.1016498108
Depolymerizing kinesins Kip3 and MCAK shape cellular microtubule architecture by differential control of catastrophe
Cell. 2011 Nov 23; 147(5):1092-103
PMID: 22118464 doi: 10.1016/j.cell.2011.10.037
2010
Microtubule dynamics reconstituted in vitro and imaged by single-molecule fluorescence microscopy
Methods of Cell Biology. 2010:95:221-45
PMID: 20466138 doi: 10.1016/S0091-679X(10)95013-9
2009
EB1 recognizes the nucleotide state of tubulin in the microtubule lattice
PLoS ONE. 2009 Oct 23; 4(10):e7585
PMID: 19851462 doi: 10.1371/journal.pone.0007585
2008
One-step isolation of plasma membrane proteins using magnetic beads with immobilized concanavalin A
Protein Expression and Purification. 2008 Dec;62(2):223-9
PMID: 18765283 doi: 10.1016/j.pep.2008.08.003