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Resistance is futile: Centering forces yield for asymmetric cell division


Alper J , Zanic M . The Journal of Cell Biology. 2019 2 15; (). [Epub ahead of print]


Asymmetric cell division relies on microtubule-based forces to asymmetrically position the mitotic apparatus. In this issue, Sallé et al. (2019. J. Cell Biol. use magnetic tweezers to induce asymmetric division in sea urchin zygotes, demonstrating that asymmetry could arise from a time-dependent weakening of centering forces.