Sandra Berndt, Ph.D.

Sandra Berndt, Ph.D.

Group Leader, Schoenheimer-Institute of Biochemistry, University of Leipzig

Background

Postdoc, Vanderbilt University

Ph.D. University of Leipzig, Germany.

M.S. University of Leipzig, Germany.

Publications From the Lab

A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr. Perez I, Berndt S, Agarwal R, Castro MA, Vishnivetskiy SA, Smith JC, Sanders CR, Gurevich VV, Iverson TM.J Mol Biol. 2022 Jan 30;434(2):167400. doi: 10.1016/j.jmb.2021.167400.

An Eight Amino Acid Segment Controls Oligomerization and Preferred Conformation of the two Non-visual Arrestins. Chen Q, Zhuo Y, Sharma P, Perez I, Francis DJ, Chakravarthy S, Vishnivetskiy SA, Berndt S, Hanson SM, Zhan X, Brooks EK, Altenbach C, Hubbell WL, Klug CS, Iverson TM, Gurevich VV.J Mol Biol. 2021 Feb 19;433(4):166790. doi: 10.1016/j.jmb.2020.166790.

Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification. Perry NA, Kaoud TS, Ortega OO, Kaya AI, Marcus DJ, Pleinis JM, Berndt S, Chen Q, Zhan X, Dalby KN, Lopez CF, Iverson TM, Gurevich VV.Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):810-815.

Crystal structure of the SH3 domain of human Lyn non-receptor tyrosine kinase. Berndt S, Gurevich VV, Iverson TM.PLoS One. 2019 Apr 10;14(4):e0215140. doi: 10.1371/journal.pone.0215140. eCollection 2019.

Structural basis of arrestin-3 activation and signaling. Chen Q, Perry NA, Vishnivetskiy SA, Berndt S, Gilbert NC, Zhuo Y, Singh PK, Tholen J, Ohi MD, Gurevich EV, Brautigam CA, Klug CS, Gurevich VV, Iverson TM.Nat Commun. 2017 Nov 10;8(1):1427. doi: 10.1038/s41467-017-01218-8.