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Pankaj Sharma, Ph.D.

Lab Instructor, Department of Pharmacology


Background

Ph.D. Institute of Microbial Technology, Chandigarh, India.

M.S. Guru Nanak Dev University, Amritsar, India.

Awards

AHA Postdoctoral Fellowship 2019-2020

Publications

Chen Q, Zhuo Y, Sharma P, Perez I, Francis DJ, Chakravarthy S, Vishnivetskiy SA, Berndt S, Hanson SM, Zhan X, Brooks EK, Altenbach C, Hubbell WL, Klug CS, Iverson TM, Gurevich VV (2021) An Eight Amino Acid Segment Controls Oligomerization and Preferred Conformation of the two Non-visual Arrestins. J Mol Biol. 433(4):166790.

Pankaj Sharma, Elena Maklashina, Gary Cecchini, TM Iverson (2020) The Roles of SDHAF2 And Dicarboxylate in Covalent flavinylation of SDHA, the Human Complex II Flavoprotein, Proc Natl Acad Sci USA, 117(38):23548-23556.

Pankaj Sharma*, Rachana Tomar*, Samir Kumar Nath, Shivpratap Singh Yadav, Maulik D. Badmalia, Ashish, Bishwajit Kundu (2020) Decoding hyperthermophilic capability of Pyrococcus Furiosus L-Asparaginase: short b-strands stitch reversible association Scientific Reports, (In   press). 

Navdeep Kaur*, Amin Sagar*, Pankaj Sharma*, Ashish Ganguly and Pratap Kumar Pati (2020)    Structural insights into rice SalTol QTL located SALT protein, Scientific Reports, 10, 16589.

Haley E. Stubbs, Barbara A. Bensing, Izumi Yamakawa, Pankaj Sharma, Hai Yu4, Xi Chen, Paul       M. Sullam, T.M. Iverson (2020) Tandem sialoglycan-binding modules in a Streptococcus sanguinis   serine-rich repeat adhesin create target dependent avidity effects, J Biol Chem. 295 (43), 14737-14749. 

Pankaj Sharma, Elena Maklashina, Gary Cecchini, TM Iverson (2019) Maturation of the respiratory complex II flavoprotein, Current Opinion in Structural Biology, 59, 38-46.

Maulik D. Badmalia, Pankaj Sharma, Shiv Pratap Singh Yadav, Shikha Singh, Neeraj Khatri, Renu Garg & Ashish (2018) Bonsai Gelsolin Survives Heat Induced Denaturation by Forming β-Amyloids which Leach Out Functional Monomer. Scientific Reports, 8, 12602.

Sharma, P., Maklashina, E., Cecchini, G., Iverson, T.M.  (2017) Crystal structure of an assembly intermediate of respiratory Complex II.  Nat Commun. 2018 Jan 18;9(1):274.

Starbird, C.A., Maklashina, E., Sharma, P., Qualls-Histed, S., Cecchini, G., Iverson, T.M. (2017) Structural and biochemical analyses reveal insights into covalent flavinylation of the Escherichia coli Complex II homolog quinol:fumarate reductase. J Biol Chem. 2017 Aug 4;292(31):12921-12933.

Sharma, P., Verma, N., Singh, P.K., Korpole, S., Ashish.  Characterization of heat induced spherulites of lysozyme provides new insight on amyloid initiation. Sci Rep. 2016 Mar 1;6:22475.

Arif, E.*, Sharma, P.*, Solanki, A., Mallik, L., Rathore, Y.S., Twal, W.O., Nath, S.K., Gandhi, D., Holzman, L.B., Ostap, E.M., Ashish, Nihalani, D.  Structural analysis of the Myo1c and Neph1 complex provides insight into the intracellular movement of Neph1. Mol Cell Biol. 2016 May 16;36(11):1639-54.

Tomar, R.*, Sharma, P.*, Srivastava, A., Bansal, S., Ashish, Kundu, B.  Structural and functional insights into an archaeal L-asparaginase obtained through the linker-less assembly of constituent domains. Acta Crystallogr D Biol Crystallogr. 2014 Dec 1;70(Pt 12):3187-97.

Mallik, L.*, Arif, E.*, Sharma, P., Rathore, Y.S., Wong, H.N., Holzman, L.B., Ashish, Nihalani, D.  Solution structure analysis of cytoplasmic domain of podocyte protein Neph1 using small/wide angle x-ray scattering (SWAXS). J Biol Chem. 2012 Mar 16;287(12):9441-53.

 

*Authors contributed equally.