Margo Goldfarb
Graduate Student, Department of Pharmacology
Background
BA and honors in Chemistry, Minor in Biology, Concentration in Scientific Computing, Emphasis in Philosophy of Science, Kenyon College, Gambier, OH
Publications from the lab
CryoEM structures reveal how the bacterial flagellum rotates and switches direction. Singh PK, Sharma P, Afanzar O, Goldfarb MH, Maklashina E, Eisenbach M, Cecchini G, Iverson TM. Nat Microbiol. 2024 May;9(5):1271-1281. doi: 10.1038/s41564-024-01674-1. Epub 2024 Apr 17. PMID: 38632342
Past publications
Synthesis of β-Alanine From Isoleucine and Propionate Catabolism via Aminotransferases. Goldfarb MH, Boesel J, Wilczewski-Shirai KC, Reinhart P, Scherger T, Webb C, Newlun M, Rouhier KA. Plant Direct. 2024 Dec 18;8(12):e70030. doi: 10.1002/pld3.70030. eCollection 2024 Dec. PMID: 39703930 F
Kinetic Evidence for an Induced Fit Mechanism in the Binding of the Substrate Camphor by Cytochrome P450cam. Guengerich FP, Child SA, Barckhausen IR, Goldfarb MH. ACS Catal. 2021 Jan 15;11(2):639-649. doi: 10.1021/acscatal.0c04455. Epub 2020 Dec 29. PMID: 34327042 Free PMC article.
Functional interactions of adrenodoxin with several human mitochondrial cytochrome P450 enzymes. Child SA, Reddish MJ, Glass SM, Goldfarb MH, Barckhausen IR, Guengerich FP. Arch Biochem Biophys. 2020 Nov 15;694:108596. doi: 10.1016/j.abb.2020.108596. Epub 2020 Sep 24. PMID: 32980349 Free PMC article.
Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102. Lewis DF, Lake BG, George SG, Dickins M, Eddershaw PJ, Tarbit MH, Beresford AP, Goldfarb PS, Guengerich FP. Toxicology. 1999 Nov 29;139(1-2):53-79. doi: 10.1016/s0300-483x(99)00098-0.