Tom Tomasiak, Ph.D.

Associate Professor (With Tenure), University of Arizona

BS, Biomedical Sciences Grand Valley State University

PhD, Pharmacology, Vanderbilt University

New crystal forms of the integral membrane Escherichia coli quinol:fumarate reductase suggest that ligands control domain movement.Starbird CA, Tomasiak TM, Singh PK, Yankovskaya V, Maklashina E, Eisenbach M, Cecchini G, Iverson TM.J Struct Biol. 2018 Apr;202(1):100-104. doi: 10.1016/j.jsb.2017.11.004. Epub 2017 Nov 20.PMID: 29158068 Free PMC article.

Plasticity of the quinone-binding site of the complex II homolog quinol:fumarate reductase.Singh PK, Sarwar M, Maklashina E, Kotlyar V, Rajagukguk S, Tomasiak TM, Cecchini G, Iverson TM.J Biol Chem. 2013 Aug 23;288(34):24293-301. doi: 10.1074/jbc.M113.487082. Epub 2013 Jul 8.PMID: 23836905 Free PMC article.

A structural model for binding of the serine-rich repeat adhesin GspB to host carbohydrate receptors.Pyburn TM, Bensing BA, Xiong YQ, Melancon BJ, Tomasiak TM, Ward NJ, Yankovskaya V, Oliver KM, Cecchini G, Sulikowski GA, Tyska MJ, Sullam PM, Iverson TM.PLoS Pathog. 2011 Jul;7(7):e1002112. doi: 10.1371/journal.ppat.1002112. Epub 2011 Jul 7.PMID: 21765814 Free PMC article.

Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.Tomasiak TM, Archuleta TL, Andréll J, Luna-Chávez C, Davis TA, Sarwar M, Ham AJ, McDonald WH, Yankovskaya V, Stern HA, Johnston JN, Maklashina E, Cecchini G, Iverson TM.J Biol Chem. 2011 Jan

A threonine on the active site loop controls transition state formation in Escherichia coli respiratory complex II.Tomasiak TM, Maklashina E, Cecchini G, Iverson TM.J Biol Chem. 2008 May 30;283(22):15460-8. doi: 10.1074/jbc.M801372200. Epub 2008 Apr 2.PMID: 18385138 Free PMC article.

Succinate as Donor; Fumarate as Acceptor. Tomasiak TM, Cecchini G, Iverson TM.EcoSal Plus. 2007 Apr;2(2). doi: 10.1128/ecosal.3.2.6.PMID: 26443593