Tim Panosian, Ph.D.
Senior Director, Enko
Background
B.S., State University of New York at Buffalo
Ph.D. Vanderbilt University
Publications from the lab
Bioretrosynthetic construction of a didanosine biosynthetic pathway. Nat Chem Biol. 2014 May;10(5):392-9. doi: 10.1038/nchembio.1494. Epub 2014 Mar 23.PMID: 24657930
Molecular differences between a mutase and a phosphatase: investigations of the activation step in Bacillus cereus phosphopentomutase.Biochemistry. 2012 Mar 6;51(9):1964-75. doi: 10.1021/bi201761h. Epub 2012 Feb 21.PMID: 22329805
Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycle.
J Biol Chem. 2011 Mar 11;286(10):8043-8054. doi: 10.1074/jbc.M110.201350. Epub 2010 Dec 30.PMID: 21193409
Crystallization and preliminary X-ray analysis of a phosphopentomutase from Bacillus cereus. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jul 1;66(Pt 7):811-4. doi: 10.1107/S1744309110017549. Epub 2010 Jun 24.PMID: 20606280
Mechanism of potassium-channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore. Nat Struct Mol Biol. 2009 Dec;16(12):1317-24. doi: 10.1038/nsmb.1703. Epub 2009 Nov 29.PMID: 19946269