Izumi Yamakawa

Nurse, Vanderbilt University Medical Center

B.A., Chemistry and Biochemistry, Oberlin College

Nursing, University of Belmont School of Nursing

Publications from the lab

Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Bensing BA, Stubbs HE, Agarwal R, Yamakawa I, Luong K, Solakyildirim K, Yu H, Hadadianpour A, Castro MA, Fialkowski KP, Morrison KM, Wawrzak Z, Chen X, Lebrilla CB, Baudry J, Smith JC, Sullam PM, Iverson TM.Nat Commun. 2022 May 18;13(1):2753. doi: 10.1038/s41467-022-30509-y.PMID: 35585145

Tandem sialoglycan-binding modules in a Streptococcus sanguinis serine-rich repeat adhesin create target dependent avidity effects. Stubbs HE, Bensing BA, Yamakawa I, Sharma P, Yu H, Chen X, Sullam PM, Iverson TM.J Biol Chem. 2020 Oct 23;295(43):14737-14749. doi: 10.1074/jbc.RA120.014177. Epub 2020 Aug 20.PMID: 32820052

An alternative N-terminal fold of the intestine-specific annexin A13a induces dimerization and regulates membrane-binding. McCulloch KM, Yamakawa I, Shifrin DA Jr, McConnell RE, Foegeding NJ, Singh PK, Mao S, Tyska MJ, Iverson TM.J Biol Chem. 2019 Mar 8;294(10):3454-3463. doi: 10.1074/jbc.RA118.004571. Epub 2019 Jan 4.