Publications

2023

Layden HM, Jones AL, Ellis JD, Hiebert SW, A dual indexed approach to small RNA sequencing library preparation for PRO-seq Research Square. 2023 Jun 30;
Bomber ML, Wang J, Liu Q, Barnett KR, Layden HM, Hodges E, Stengel KR, Hiebert SW, Human SMARCA5 is continuously required to maintain nucleosome spacing Molecular Cell. 2023 Feb 16;

2022

Zhang S, Wang J, Liu Q, McDonald WH, Bomber ML, Layden HM, Ellis JD, Borinstein SC, Hiebert SW, Stengel KR, PAX3-FOXO1 coordinates enhancer architecture, eRNA transcription, and RNA polymerase pause release at select gene targets Molecular Cell. 2022 Dec 1;
Brown RE, Jacobse J, Anant SA, Blunt KM, Chen B, Vega PN, Jones CT, Pilat JM, Revetta F, Gorby AH, Stengel KR, Choski YA, Palin K, Piazuelo MB, Washington MK, Lau KS, Goettel JA, Williams CS, MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors JCI Insight. 2022 May 23;

2021

Ramsey HE, Stengel KR, Pino JC, Johnston G, Childress M, Gorska AE, Arrate PM, Fuller L, Villaume M, Fischer MA, Ferrell PB, Roe CE, Zhou J, Lubbock ALR, Stubbs M, Zinkel S, Irish JM, Lopez CF, Hiebert SW, Savona MR, Selective Inhibition of JAK1 Primes STAT5-Driven Human Leukemia Cells for ATRA-Induced Differentiation Targeted Oncology. 2021 Sep 16;
Stengel KR, Ellis JD, Spielman CL, Bomber ML, Layden SW, Definition of a small core transcriptional circuit regulated by AML1-ETO Molecular Cell. 2021 Dec 30;

2020

Ramsey HE, Greenwood D, Zhang S, Childress M, Arrate MP, Gorska AE, Fuller L, Zhao Y, Stengel KR, Fischer MA, Stubbs MC, Liu PC, Boyd K, Rathmell JC, Hiebert SW, Savona MR, BET Inhibition Enhances the Antileukemic Activity of Low-dose Venetoclax in Acute Myeloid Leukemia Clinical Cancer Research. 2020 Nov 4;
Johnston G., Ramsey H., Liu Q., Wang J., Stengel K. R., Sampathi S., Arharya P., Arrate M., Stubbs M. C., Burn T., Savona M. R., Hiebert S. W., Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia Gene. 2020 May 15;

2019

Stengel K.R., Bhaskara S., Wang J., Liu Q., Ellis J.D., Sampathi S., Hiebert S.W., Histone deacetylase 3 controls a transcriptional network required for B cell maturation Nucleic Acids Research. 2019 Oct 5; 47 (20) 10612-10627
Sampathi S, Acharya P, Zhao Y, Wang J, Stengel KR, Liu Q, Savona MR, Hiebert SW, The CDK7 inhibitor THZ1 alters RNA polymerase dynamics at the 5′ and 3′ ends of genes Nucleic acids research. 2019 May 7; 47 (8) 3921-3936
Short SP, Barrett CW, Stengel KR, Revetta FL, Choksi YA, Coburn LA, Lintel MK, McDonough EM, Washington MK, Wilson KT, Prokhortchouk E, Chen X, Hiebert SW, Reynolds AB, Williams CS, Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma Oncogene. 2019 Mar 11; 38 (25) 5091-5106
Aho E.R., Wang J., Gogliotti R.D., Howard G.C., Phan J., Acharya P., Macdonald J.D., Cheng K., Lorey L., Lu B., Wenzel S., Foshage A.M., Alvarado J., Wang F., Shaw J.G., Zhao B., Weissmiller A.M., Thomas L.R., Vakoc C.R., Hall M.D., Hiebert S.W., Liu Q., Stauffer S.R., Fesik S.W., Tansey W.P., Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Reports. 2019 Mar 12; 26 (11) 2916-2928

2018

Wang J, Zhao Y, Zhou X, Hiebert SW, Liu Q, Shyr Y, Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation BMC genomics. 2018 Aug 23; 19 (1) 633
Zhang S, Zhao Y, Heaster TM, Fischer MA, Stengel KR, Zhou X, Ramsey H, Zhou MM, Savona MR, Skala MC, Hiebert SW, BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML Journal of cellular biochemistry. 2018 Nov 11;

2017

Liu Q, Wang J, Zhao Y, Li CI, Stengel KR, Acharya P, Johnston G, Hiebert SW, Shyr Y, Identification of active miRNA promoters from nuclear run-on RNA sequencing Nucleic acids research. 2017 Jul 27; 45 (13) e121
Heaster TM, Walsh AJ, Zhao Y, Hiebert SW, Skala MC, Autofluorescence imaging identifies tumor cell-cycle status on a single-cell level Journal of biophotonics. 2017 May 09; 11 (1)
Ferrari A, Longo R, Fiorino E, Silva R, Mitro N, Cermenati G, Gilardi F, Desvergne B, Andolfo A, Magagnotti C, Caruso D, Fabiani E, Hiebert SW, Crestani M, HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning Nature communications. 2017 Jul 21; 8 (1) 93
Stengel KR, Barnett KR, Wang J, Liu Q, Hodges E, Hiebert SW, Bhaskara S, Deacetylase activity of histone deacetylase 3 is required for productive recombination and B-cell development Proceedings of the National Academy of Sciences of the United States of America. 2017 Jul 24; 114 (32) 8608-8613
McDonough EM, Barrett CW, Parang B, Mittal MK, Smith JJ, Bradley AM, Choksi YA, Coburn LA, Short SP, Thompson JJ, Zhang B, Poindexter SV, Fischer MA, Chen X, Li J, Revetta FL, Naik R, Washington MK, Rosen MJ, Hiebert SW, Wilson KT, Williams CS, MTG16 is a tumor suppressor in colitis-associated carcinoma JCI insight. 2017 Aug 17; 2 (16)

2016

Chan E, Arlinghaus LR, Cardin DB, Goff L, Berlin JD, Parikh A, Abramson RG, Yankeelov TE, Hiebert S, Merchant N, Bhaskara S, Chakravarthy AB, Phase I trial of vorinostat added to chemoradiation with capecitabine in pancreatic cancer Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2016 Apr 19; 119 (2) 312-8
Hargrove TY, Friggeri L, Wawrzak Z, Sivakumaran S, Yazlovitskaya EM, Hiebert SW, Guengerich FP, Waterman MR, Lepesheva GI, Human sterol 14α-demethylase as a target for anticancer chemotherapy: towards structure-aided drug design Journal of lipid research. 2016 Jun 16; 57 (8) 1552-63
Zhao Y, Liu Q, Acharya P, Stengel KR, Sheng Q, Zhou X, Kwak H, Fischer MA, Bradner JE, Strickland SA, Mohan SR, Savona MR, Venters BJ, Zhou MM, Lis JT, Hiebert SW, High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML Cell reports. 2016 Aug 04; 16 (7) 2003-16
Cho SH, Raybuck AL, Stengel K, Wei M, Beck TC, Volanakis E, Thomas JW, Hiebert S, Haase VH, Boothby MR, Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system Nature. 2016 Aug 08; 537 (7619) 234-238
Jiang Y, Ortega-Molina A, Geng H, Ying HY, Hatzi K, Parsa S, McNally D, Wang L, Doane AS, Agirre X, Teater M, Meydan C, Li Z, Poloway D, Wang S, Ennishi D, Scott DW, Stengel KR, Kranz JE, Holson E, Sharma S, Young JW, Chu CS, Roeder RG, Shaknovich R, Hiebert SW, Gascoyne RD, Tam W, Elemento O, Wendel HG, Melnick AM, CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas Cancer discovery. 2016 Oct 12; 7 (1) 38-53

2015

Poindexter SV, Reddy VK, Mittal MK, Williams AM, Washington MK, Harris E, Mah A, Hiebert SW, Singh K, Chaturvedi R, Wilson KT, Lund PK, Williams CS, Transcriptional corepressor MTG16 regulates small intestinal crypt proliferation and crypt regeneration after radiation-induced injury American journal of physiology. Gastrointestinal and liver physiology. 2015 Jan 08; 308 (6) G562-71
Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M, Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells Cell stem cell. 2015 May 7; 16 (5) 477-87
Hsu FC, Belmonte PJ, Constans MM, Chen MW, McWilliams DC, Hiebert SW, Shapiro VS, Histone Deacetylase 3 Is Required for T Cell Maturation Journal of immunology (Baltimore, Md. : 1950). 2015 Jul 10; 195 (4) 1578-90
Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW, FOXP3⁺ regulatory T cell development and function require histone/protein deacetylase 3 The Journal of clinical investigation. 2015 Aug 03; 125 (8) 3304
Stengel KR, Zhao Y, Klus NJ, Kaiser JF, Gordy LE, Joyce S, Hiebert SW, Summers AR, Histone Deacetylase 3 Is Required for Efficient T Cell Development Molecular and cellular biology. 2015 Aug 31; 35 (22) 3854-65
Adams CM, Hiebert SW, Eischen CM, Myc Induces miRNA-Mediated Apoptosis in Response to HDAC Inhibition in Hematologic Malignancies Cancer research. 2015 Dec 16; 76 (3) 736-48

2014

Stengel KR, Hiebert SW, Class I HDACs Affect DNA Replication, Repair, and Chromatin Structure: Implications for Cancer Therapy Antioxidants & redox signaling. 2014 Jun 26; 23 (1) 51-65
Ghosh HS, Ceribelli M, Matos I, Lazarovici A, Bussemaker HJ, Lasorella A, Hiebert SW, Liu K, Staudt LM, Reizis B, ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2 The Journal of experimental medicine. 2014 Jun 30; 211 (8) 1623-35
Parang B, Rosenblatt D, Williams AD, Washington MK, Revetta F, Short SP, Reddy VK, Hunt A, Shroyer NF, Engel ME, Hiebert SW, Williams CS, The transcriptional corepressor MTGR1 regulates intestinal secretory lineage allocation FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2014 Nov 14; 29 (3) 786-95

2013

Yan L, Womack B, Wotton D, Guo Y, Shyr Y, Davé U, Li C, Hiebert S, Brandt S, Hamid R, Tgif1 regulates quiescence and self-renewal of hematopoietic stem cells Molecular and cellular biology. 2013 Oct 07; 33 (24) 4824-33
Ziesché E, Kettner-Buhrow D, Weber A, Wittwer T, Jurida L, Soelch J, Müller H, Newel D, Kronich P, Schneider H, Dittrich-Breiholz O, Bhaskara S, Hiebert SW, Hottiger MO, Li H, Burstein E, Schmitz ML, Kracht M, The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB… Nucleic acids research. 2013 Jan 7; 41 (1) 90-109
Williams CS, Bradley AM, Chaturvedi R, Singh K, Piazuelo MB, Chen X, McDonough EM, Schwartz DA, Brown CT, Allaman MM, Coburn LA, Horst SN, Beaulieu DB, Choksi YA, Washington MK, Williams AD, Fisher MA, Zinkel SS, Peek RM, Wilson KT, Hiebert SW, MTG16 contributes to colonic epithelial integrity in experimental colitis. Gut. 2013 Oct 62 (10) 1446-55
Wells CE, Bhaskara S, Stengel KR, Zhao Y, Sirbu B, Chagot B, Cortez D, Khabele D, Chazin WJ, Cooper A, Jacques V, Rusche J, Eischen CM, McGirt LY, Hiebert SW, Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma. PloS one. 2013 8 (7) e68915
Hatzi K, Jiang Y, Huang C, Garrett-Bakelman F, Gearhart MD, Giannopoulou EG, Zumbo P, Kirouac K, Bhaskara S, Polo JM, Kormaksson M, MacKerell AD, Xue F, Mason CE, Hiebert SW, Prive GG, Cerchietti L, Bardwell VJ, Elemento O, Melnick A, A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct compl… Cell reports. 2013 Aug 15; 4 (3) 578-88
Summers AR, Fischer MA, Stengel KR, Zhao Y, Kaiser JF, Wells CE, Hunt A, Bhaskara S, Luzwick JW, Sampathi S, Chen X, Thompson MA, Cortez D, Hiebert SW, HDAC3 is essential for DNA replication in hematopoietic progenitor cells. The Journal of clinical investigation. 2013 Jul 1; 123 (7) 3112-23

2012

Fischer MA, Moreno-Miralles I, Hunt A, Chyla BJ, Hiebert SW, Myeloid translocation gene 16 is required for maintenance of haematopoietic stem cell quiescence. The EMBO journal. 2012 Mar 21; 31 (6) 1494-505
Barrett CW, Smith JJ, Lu LC, Markham N, Stengel KR, Short SP, Zhang B, Hunt AA, Fingleton BM, Carnahan RH, Engel ME, Chen X, Beauchamp RD, Wilson KT, Hiebert SW, Reynolds AB, Williams CS, Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters. PloS one. 2012 7 (12) e51205

2011

Hunt A, Fischer M, Engel ME, Hiebert SW, Mtg16/Eto2 contributes to murine T-cell development. Molecular and cellular biology. 2011 Jul 31 (13) 2544-51
Bhaskara S, Hiebert SW, Role for histone deacetylase 3 in maintenance of genome stability. Cell cycle (Georgetown, Tex.). 2011 Mar 1; 10 (5) 727-8
Barrett CW, Fingleton B, Williams A, Ning W, Fischer MA, Washington MK, Chaturvedi R, Wilson KT, Hiebert SW, Williams CS, MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model. Cancer research. 2011 Feb 15; 71 (4) 1302-12
Zheng S, Tansey WP, Hiebert SW, Zhao Z, Integrative network analysis identifies key genes and pathways in the progression of hepatitis C vir… BMC medical genomics. 2011 4 62
Sirbu BM, Couch FB, Feigerle JT, Bhaskara S, Hiebert SW, Cortez D, Analysis of protein dynamics at active, stalled, and collapsed replication forks. Genes & development. 2011 Jun 15; 25 (12) 1320-7
Wilson AJ, Holson E, Wagner F, Zhang YL, Fass DM, Haggarty SJ, Bhaskara S, Hiebert SW, Schreiber SL, Khabele D, The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in … Cancer biology & therapy. 2011 Sep 15; 12 (6) 484-93

2010

Razidlo DF, Whitney TJ, Casper ME, McGee-Lawrence ME, Stensgard BA, Li X, Secreto FJ, Knutson SK, Hiebert SW, Westendorf JJ, Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increase… PloS one. 2010 5 (7) e11492
Engel ME, Hiebert SW, Proleukemic RUNX1 and CBFbeta mutations in the pathogenesis of acute leukemia. Cancer treatment and research. 2010 145 127-47
Engel ME, Nguyen HN, Mariotti J, Hunt A, Hiebert SW, Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integ… Molecular and cellular biology. 2010 Apr 30 (7) 1852-63
Compton LA, Hiebert SW, Anticancer therapy SMRT-ens up: targeting the BCL6-SMRT interaction in B cell lymphoma. Cancer cell. 2010 Apr 13; 17 (4) 315-6
Engel ME, Hiebert SW, The enemy within: dormant retroviruses awaken. Nature medicine. 2010 May 16 (5) 517-8
Huang F, Chandrasekharan MB, Chen YC, Bhaskara S, Hiebert SW, Sun ZW, The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) fing… The Journal of biological chemistry. 2010 Aug 6; 285 (32) 24548-61
Bhaskara S, Knutson SK, Jiang G, Chandrasekharan MB, Wilson AJ, Zheng S, Yenamandra A, Locke K, Yuan JL, Bonine-Summers AR, Wells CE, Kaiser JF, Washington MK, Zhao Z, Wagner FF, Sun ZW, Xia F, Holson EB, Khabele D, Hiebert SW, Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer cell. 2010 Nov 16; 18 (5) 436-47

2009

Yan M, Ahn EY, Hiebert SW, Zhang DE, RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leuke… Blood. 2009 Jan 22; 113 (4) 883-6
Cai Y, Xu Z, Xie J, Ham AJ, Koury MJ, Hiebert SW, Brandt SJ, Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine ery… Biochemical and biophysical research communications. 2009 Dec 11; 390 (2) 295-301

2008

Chyla BJ, Moreno-Miralles I, Steapleton MA, Thompson MA, Bhaskara S, Engel M, Hiebert SW, Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and line… Molecular and cellular biology. 2008 Oct 28 (20) 6234-47
Hanson CA, Wood LD, Hiebert SW, Cellular stress triggers TEL nuclear export via two genetically separable pathways. Journal of cellular biochemistry. 2008 May 15; 104 (2) 488-98
Bhaskara S, Chyla BJ, Amann JM, Knutson SK, Cortez D, Sun ZW, Hiebert SW, Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage contr… Molecular cell. 2008 Apr 11; 30 (1) 61-72
Knutson SK, Chyla BJ, Amann JM, Bhaskara S, Huppert SS, Hiebert SW, Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks. The EMBO journal. 2008 Apr 9; 27 (7) 1017-28
Moore AC, Amann JM, Williams CS, Tahinci E, Farmer TE, Martinez JA, Yang G, Luce KS, Lee E, Hiebert SW, Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dep… Molecular and cellular biology. 2008 Feb 28 (3) 977-87
Farmer TE, Williams CS, Washington MK, Hiebert SW, Inactivation of the p19(ARF) tumor suppressor affects intestinal epithelial cell proliferation and i… Journal of cellular biochemistry. 2008 Aug 15; 104 (6) 2228-40

2007

Yang G, Thompson MA, Brandt SJ, Hiebert SW, Histone deacetylase inhibitors induce the degradation of the t(8;21) fusion oncoprotein. Oncogene. 2007 Jan 4; 26 (1) 91-101

2006

Reed-Inderbitzin E, Moreno-Miralles I, Vanden-Eynden SK, Xie J, Lutterbach B, Durst-Goodwin KL, Luce KS, Irvin BJ, Cleary ML, Brandt SJ, Hiebert SW, RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription. Oncogene. 2006 Sep 21; 25 (42) 5777-86
Martinez JA, Williams CS, Amann JM, Ellis TC, Moreno-Miralles I, Washington MK, Gregoli P, Hiebert SW, Deletion of Mtgr1 sensitizes the colonic epithelium to dextran sodium sulfate-induced colitis. Gastroenterology. 2006 Aug 131 (2) 579-88

2005

Yang G, Khalaf W, van de Locht L, Jansen JH, Gao M, Thompson MA, van der Reijden BA, Gutmann DH, Delwel R, Clapp DW, Hiebert SW, Transcriptional repression of the Neurofibromatosis-1 tumor suppressor by the t(8;21) fusion protein… Molecular and cellular biology. 2005 Jul 25 (14) 5869-79
Amann JM, Chyla BJ, Ellis TC, Martinez A, Moore AC, Franklin JL, McGhee L, Meyers S, Ohm JE, Luce KS, Ouelette AJ, Washington MK, Thompson MA, King D, Gautam S, Coffey RJ, Whitehead RH, Hiebert SW, Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineag… Molecular and cellular biology. 2005 Nov 25 (21) 9576-85
Ice RJ, Wildonger J, Mann RS, Hiebert SW, Comment on “Nervy links protein kinase A to plexin-mediated semaphorin repulsion”. Science (New York, N.Y.). 2005 Jul 22; 309 (5734) 558; author reply 558

2004

Irvin BJ, Hiebert SW, AML-1 steps up to the platelets. Nature medicine. 2004 Mar 10 (3) 238-9
Müller-Tidow C, Steffen B, Cauvet T, Tickenbrock L, Ji P, Diederichs S, Sargin B, Köhler G, Stelljes M, Puccetti E, Ruthardt M, deVos S, Hiebert SW, Koeffler HP, Berdel WE, Serve H, Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic… Molecular and cellular biology. 2004 Apr 24 (7) 2890-904

2003

Irvin BJ, Wood LD, Wang L, Fenrick R, Sansam CG, Packham G, Kinch M, Yang E, Hiebert SW, TEL, a putative tumor suppressor, induces apoptosis and represses transcription of Bcl-XL. The Journal of biological chemistry. 2003 Nov 21; 278 (47) 46378-86
Wood LD, Irvin BJ, Nucifora G, Luce KS, Hiebert SW, Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppress… Proceedings of the National Academy of Sciences of the United States of America. 2003 Mar 18; 100 (6) 3257-62

2002

Linggi B, Müller-Tidow C, van de Locht L, Hu M, Nip J, Serve H, Berdel WE, van der Reijden B, Quelle DE, Rowley JD, Cleveland J, Jansen JH, Pandolfi PP, Hiebert SW, The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor… Nature medicine. 2002 Jul 8 (7) 743-50

2001

Amann JM, Nip J, Strom DK, Lutterbach B, Harada H, Lenny N, Downing JR, Meyers S, Hiebert SW, ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylas… Molecular and cellular biology. 2001 Oct 21 (19) 6470-83

2000

Strom DK, Nip J, Westendorf JJ, Linggi B, Lutterbach B, Downing JR, Lenny N, Hiebert SW, Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle. The Journal of biological chemistry. 2000 Feb 4; 275 (5) 3438-45
Melnick A, Carlile GW, McConnell MJ, Polinger A, Hiebert SW, Licht JD, AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promy… Blood. 2000 Dec 1; 96 (12) 3939-47
Lutterbach B, Westendorf JJ, Linggi B, Isaac S, Seto E, Hiebert SW, A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocat… The Journal of biological chemistry. 2000 Jan 7; 275 (1) 651-6
Fenrick R, Wang L, Nip J, Amann JM, Rooney RJ, Walker-Daniels J, Crawford HC, Hulboy DL, Kinch MS, Matrisian LM, Hiebert SW, TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells… Molecular and cellular biology. 2000 Aug 20 (16) 5828-39

1999

Lutterbach B, Hou Y, Durst KL, Hiebert SW, The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor. Proceedings of the National Academy of Sciences of the United States of America. 1999 Oct 26; 96 (22) 12822-7
Fenrick R, Amann JM, Lutterbach B, Wang L, Westendorf JJ, Downing JR, Hiebert SW, Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein. Molecular and cellular biology. 1999 Oct 19 (10) 6566-74

1998

Westendorf JJ, Yamamoto CM, Lenny N, Downing JR, Selsted ME, Hiebert SW, The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent t… Molecular and cellular biology. 1998 Jan 18 (1) 322-33

1996

Hiebert SW, Sun W, Davis JN, Golub T, Shurtleff S, Buijs A, Downing JR, Grosveld G, Roussell MF, Gilliland DG, Lenny N, Meyers S, The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription. Molecular and cellular biology. 1996 Apr 16 (4) 1349-55
Okuda T, van Deursen J, Hiebert SW, Grosveld G, Downing JR, AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal f… Cell. 1996 Jan 26; 84 (2) 321-30

1995

Meyers S, Lenny N, Hiebert SW, The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation. Molecular and cellular biology. 1995 Apr 15 (4) 1974-82

1993

Meyers S, Downing JR, Hiebert SW, Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-bi… Molecular and cellular biology. 1993 Oct 13 (10) 6336-45

1992

Hiebert SW, Chellappan SP, Horowitz JM, Nevins JR, The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. Genes & development. 1992 Feb 6 (2) 177-85

1991

Mudryj M, Devoto SH, Hiebert SW, Hunter T, Pines J, Nevins JR, Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A. Cell. 1991 Jun 28; 65 (7) 1243-53