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The hyperglycemic byproduct methylglyoxal impairs anticoagulant activity through covalent adduction of antithrombin III.


AUTHORS

Jacobson R , Mignemi N , Rose K , O'Rear L , Sarilla S , Hamm HE , Barnett JV , Verhamme IM , Schoenecker J . Thrombosis Research. 2014 12 ; 134(6). 1350-7

ABSTRACT