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Our research program aims to reveal new molecular mechanisms involved in regulating cell fate.  The lab focuses on three main lines of research:

  1. Mechanisms by which mitochondrial biology regulates normal and cancer stem cell fate. Role of the BCL-2 family of proteins modulating mitochondrial morphology/function, stem cell self-renewal, pluripotency and differentiation
  2. Examining the role of MCL-1 in early human neural development using 3D tissues
  3. Function of the ubiquitin ligase CUL9 in the transition from a stem cell to a neural progenitor cell