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We are part of a new NCI program to study the Origins of Gastroesophageal Cancers!
Oct. 12, 2022—This NCI program (funded through RFA-CA-21-026/RFA-CA-21-027) is designed to examine and define the earliest biological changes in malignant transformation. It builds on recent molecular classifications of gastroesophageal cancers, understanding of their cancer genomics, and advances in stem cell research to decipher how these cancers initially evolve at the cellular level. The initiative addresses the complex mechanisms...
We welcome Youngwon!
Aug. 29, 2022—We welcome Youngwon, a new postdoc in the lab! He will investigate molecular mechanisms driving cell lineage diversification and evolution of dysplasia to adenocarcinoma.
New R01 awarded!
Aug. 29, 2022—The Choi lab is really excited to start a brand new, second, R01 in September! We want more postdocs! If anyone is interested in cell of origin of gastric cancer or metaplastic cell plasticity, please contact Eunyoung Choi, eunyoung.choi@vumc.org.
A big congratulations to Alexis!
Aug. 29, 2022—Alexis successfully passed her oral qualifying exam! Way to go!
One more paper in 2022!
Jun. 16, 2022—Dysplastic stem cell plasticity functions as a driving force for neoplastic transformation of pre-cancerous gastric mucosa https://www.gastrojournal.org/article/S0016-5085(22)00626-6/fulltext https://pubmed.ncbi.nlm.nih.gov/35700772/
Check this out! New paper!
May. 11, 2022—Our latest international collaborative work on the function of p57Kip2 in chief cell plasticity is just out in Cell Stem Cell. https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(22)00154-0
Eunyoung is the Funderburg award 2022 recipient!
May. 4, 2022— The AGA Research Foundation awards $2.56 million in research funding
Check our our new publication!
Sep. 8, 2021—Title Chief cell plasticity is the origin of metaplasia following acute injury in the stomach mucosa Published in Gut, September 2021 DOI 10.1136/gutjnl-2021-325310 Authors Caldwell, Brianna, Meyer, Anne R, Weis, Jared A, Engevik, Amy C, Choi, Eunyoung https://gut.bmj.com/content/early/2021/09/07/gutjnl-2021-325310