Recommendations
General Recommendations
| 1H (typical samples) | Any spectrometer |
| 1H (very dilute samples) | 600 MHz [Marlin] |
| 13C NMR | The 600 MHz [Marlin] cryoprobe is ca. 4x more sensitive than all others |
| 31P,29Si,11B NMR etc | 400 MHz [Snook], 400 MHz [Perch], 400 MHz [MRBIV] or 500 MHz [Biomol] (Note: 31P is less sensitive on 400 MHz [Snook]) |
| 19F NMR | 400 MHz [Snook], 400 MHz [Perch], 400 MHz [MRBIV] or 500 MHz [Biomol] (Note: 19F is slightly less sensitive on 400 MHz [Perch]) |
Summary of Capabilities by Spectrometer
400 MHz [Snook]
| Current Probe | 5 mm broadband 3-channel (HPX) probe |
| Unique | Double decoupling experiments with 31P (e.g. 13C with 1H and 31P decoupling) |
| Best | High abundance heteronuclei (31P, 19F, 29Si, 11B) |
| Routine | 1H experiments, 1H-detected 2-dimensional experiments (e.g. COSY, HMBC etc) |
| Acceptable | X-channel nuclei (13C, 31P, etc) |
400 MHz [Perch]
| Current Probe | 5 mm broadband 3-channel (HFX) probe |
| Unique | Double decoupling experiments with 19F (e.g. 13C with 1H and 19F decoupling) |
| Best | High abundance heteronuclei (31P, 29Si, 11B) |
| Routine | 1H experiments, 1H-detected 2-dimensional experiments (e.g. COSY, HMBC etc) |
| Acceptable | 19F experiments, X-channel nuclei (13C, 31P, etc) |
600 MHz [Marlin]
| Current Probe | 5 mm TCI (inverse) cryoprobe |
| Best | 1-dimensional 1H and 1H-detected 2-dimensional experiments (e.g. COSY, HMBC etc) |
| Excellent | 13C |
| Not Possible | All nuclei other than 1H, 13C or 15N |
400 MHz [MRBIV]
| Current Probe | 5 mm broadband (BBFO) probe |
| Best | High abundance heteronuclei (31P, 19F, 29Si, 11B) |
| Acceptable | 1H experiments, H-detected 2-dimensional experiments (e.g. COSY, HMBC etc), 13C NMR |
500 MHz [Biomolec]
| Current Probe | 5 mm broadband (BBFO) probe |
| Best | High abundance heteronuclei (31P, 19F, 29Si, 11B) |
| Acceptable | 1H experiments, H-detected 2-dimensional experiments (e.g. COSY, HMBC etc), 13C NMR |
| Additional | Can be used with tall NMR tubes |