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Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M positive allosteric modulator (PAM) chemotype


AUTHORS

Temple KJKayla J , Engers JLJulie L , Long MFMadeline F , Watson KJKatherine J , Chang SSichen , Luscombe VBVincent B , Jenkins MTMatthew T , Rodriguez ALAlice L , Niswender CMColleen M , Bridges TMThomas M , Conn PJP Jeffrey , Engers DWDarren W , Lindsley CWCraig W . Bioorganic & medicinal chemistry letters. 2019 11 13; 30(3). 126812

ABSTRACT



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