Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: Potential role in liver fibrosis.
AUTHORS
Amara
SSuneetha ,
Lopez
K Karina ,
Banan
B Babak ,
Brown
SK Sade-Kemi ,
Whalen
M Margaret ,
Myles
E Elbert ,
Ivy
MT Michael T ,
Johnson
T Terrance ,
Schey
KL Kevin L ,
Tiriveedhi
V Venkataswarup .
Molecular immunology. 2015 3 ; 64(1).
26-35
- PMID: 25467797[PubMed].
- PMCID: PMC4282823.
- NIHMSID: NIHMS639707
ABSTRACT
The pro-inflammatory cytokines, tumor necrosis factor (TNF)-α, and interleukin (IL)-17, have been implicated in the pathogenesis of liver fibrosis. In this study, we investigated the role of TNFα and IL-17 toward induction of profibrotic factor, periostin.
The pro-inflammatory cytokines, tumor necrosis factor (TNF)-α, and interleukin (IL)-17, have been implicated in the pathogenesis of liver fibrosis. In this study, we investigated the role of TNFα and IL-17 toward induction of profibrotic factor, periostin.
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