Differential cyclooxygenase expression levels and survival associations in type I and type II ovarian tumors

Authors

Beeghly-Fadiel A , Wilson AJ , Keene S , El Ramahi M , Xu S , Marnett LJ , Fadare O , Crispens MA , Khabele D .
Journal of Ovarian Research. 2018 2 27; 17(11 (1)).

Abstract

High cyclooxygenase (COX)-2 expression in ovarian tumors has been associated with poor prognosis, but the role of COX-1 expression and its relation to survival is less clear. Here, we evaluated COX expression and associations with survival outcomes between type I (clear cell, mucinous, low grade endometrioid and low grade serous) and type II (high grade serous and high grade endometrioid) ovarian tumors.