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The Locke Biosensing Lab develops novel optical biosensing platforms to address current clinical diagnostic challenges at the point-of-care. We explore the use of various nanoplasmonic structures incorporated paper- or micro-fluidic platforms to create rapid diagnostic platforms that are simplistic and user-friendly.

Research Focus Areas:

1) The design and synthesis of novel bioassays for sensing of bioanalytes within complex biological fluids

2) The development and application of various portable Biophotonics-based spectroscopic tools for point-of-care sensing: surface-enhanced Raman spectroscopy, Fluorescence spectroscopy, colorimetry, etc.

3) The design of lowcost, fluidic platform: paperfluidic, microfluidics, 3D printing, microencapsulation


We are seeking a Postdoc with expertise in surface-enhanced Raman spectroscopy and/or biosensor design. 

We are currently recruiting for projects in:

  1. Identification of salivary biomarkers for eosinophilic esophagitis monitoring
  2. Low-cost, separation and characterization of pathogens
  3. Development of an at-home monitoring tool for early detection bacterial infection
  4. Development of a mobile and paper-based platform for local-surface plasmon resonance sensing

For more information, please email