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Matthew Cottam

Graduate Student, Molecular Physiology and Biophysics

Research Description

My project is to study adaptive immunity in the context of weight loss and weight regain, which we refer to as weight cycling. To date, little work has been done to describe and define changes in T cell activity within adipose tissue during significant weight changes. In the Hasty lab, I am working to understand the complex interplay between adipocytes, macrophages, and  T cells that induces adipose tissue T cell accumulation, activation, tolerance, and hypersensitivity.