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Hasty Laboratory

Are you curious about Obesity Research in the news?

Take a look at what we have published

Our work made the cover of JLB, accompanied by an Editorial. Check it out!

Our work was featured in the Vanderbilt Newsletter

Honors and Awards

Dr. Hasty discusses life in lab

Art provided for the Hasty Lab by: Liyan Shen

Our recent Original Articles:

Multiomics reveals persistence of obesity-associated immune cell phenotypes in adipose tissue during weight loss and subsequent weight regain
Myeloid-specific deletion of ferroportin impairs macrophage bioenergetics but is disconnected from systemic insulin action in adult mice
CD8+ T Cells regulate liver injury in obesity-related nonalcoholic fatty liver disease
Impaired insulin signaling in the B10.D2-Hc0 H2d H2-T18c/oSnJ mouse model of complement factor 5 (C5) deficiency.
Obesity-induced reduction of adipose eosinophils is reversed with low-calorie dietary intervention.
MFehi adipose tissue macrophages compensate for tissue iron perturbations in mice.
Elevating adipose eosinophils in obese mice to physiologically normal levels does not rescue metabolic impairments.
Obesity Alters B Cell and Macrophage Populations in Brown Adipose Tissue.
Activation of NF-κB drives the enhanced survival of adipose tissue macrophages in an obesogenic environment.
Obesity alters adipose tissue macrophage iron content and tissue iron distribution.
Weight cycling increases T-cell accumulation in adipose tissue and impairs systemic glucose tolerance.

Hear about our research

JoVE Video: Isolation of Adipose Tissue Immune Cells

Our recent Review Articles:

Fat and Iron Don’t Mix
Adipose Tissue Macrophages: Unique Polarization and Bioenergetics in Obesity
Regulation of Tissue Iron Homeostasis: the Macrophage “Ferrostat”.
Extrinsic and Intrinsic Immunometabolism Converge: Perspectives on Future Research and Therapeutic Development for Obesity
Contributions of Innate Type 2 Inflammation to Adipose Function
Links between Immunologic Memory and Metabolic Cycling
Iron homeostasis: a new job for macrophages in adipose tissue?
A decade of progress in adipose tissue macrophage biology.
What have we really learned about macrophage recruitment to adipose tissue?
A possible secondary immune response in adipose tissue during weight cycling: The ups and downs of yo-yo dieting.

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