Preprints
Conwell SC, Dahmen SN, Cranford MT, Mulvaney RJ, Long DT, Cortez D, Dewar JM. Resolution of collapsed forks is separate from completion of DNA synthesis. bioRxiv. 2025. DOI: 10.1101/2025.03.03.641087.
Peer-Reviewed
Cranford MT, Dahmen SN, Cortez D, Dewar JM. Leading and lagging strand abasic sites differentially affect vertebrate replisome progression but involve analogous bypass mechanisms. Nucleic Acids Res. 2025 Sep 23; 53(18):gkaf975.
Vontalge EJ, Kavlashvili T, Dahmen SN, Cranford MT, Dewar JM. Control of DNA replication in vitro using a reversible replication barrier. Nat Protoc. 2024 Apr 8; DOI: 10.1038/s41596-024-00977-1
Campos LV, Van Ravenstein SX, Vontalge EJ, Greer BH, Heintzman DR, Kavlashvili T, McDonald WH, Lindsey Rose K, Eichman F, Dewar JM. RTEL1 and MCM10 overcome topological stress during vertebrate replication termination. Cell Rep. 2023 Feb 28;42(2):112109
Kavlashvili K, Liu W, Mohamed TM, Cortez D, Dewar JM. Replication fork uncoupling causes nascent strand degradation and fork reversal. Nat Struct Mol Biol. 2023 Jan 2;30(1):115-124
Van Ravenstein SX, Mehta KP, Kavlashvili T, Byl JAW, Zhao R, Osheroff N, Cortez D, Dewar JM. Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms. EMBO J. 2022 Jun 14;41(12):e110632.
Heintzman DR, Campos LV, Byl JAW, Osheroff N, Dewar JM. Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination. Cell Rep. 2019 Oct 8;29(2):422-436.e5.
Parisis N, Krasinska L, Harker B, Urbach S, Rossignol M, Camasses A, Dewar J, Morin N, Fisher D. Initiation of DNA replication requires actin dynamics and formin activity. EMBO J. 2017 Nov 2;36(21):3212-3231
Reviews and Book Chapters
Conwell SC, Cranford MT, Kavlashvili T, Dewar JM. Replication fork collapse in vitro using Xenopus egg extracts. Methods Enzymol. 2022;672:317-338.
Kavlashvili T, Dewar JM. Approaches to Monitor Termination of DNA Replication Using Xenopus Egg Extracts. Methods Mol Biol. 2022;2444:105-123.
Dewar JM, Walter JC. Mechanisms of DNA replication termination. Nat Rev Mol Cell Biol. 2017;18(8):507-516.
James Dewar’s Graduate and post-doctoral publications:
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