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James Dewar’s Publications

Post-doctoral work


Vrtis KB, Dewar JM, Chistol G, Wu RA, Graham TGW, Walter JC. Single-strand DNA breaks cause replisome disassembly. Mol Cell. 2021 Mar 18.

Dewar JM, Low E, Mann M, Räschle M, Walter JC. CRL2Lrr1 promotes unloading of the vertebrate replisome from chromatin during replication termination. Genes Dev. 2017 Feb 1.

Dewar JM, Budzowska M, Walter JC. The mechanism of DNA replication termination in vertebrates. Nature. 2015 Sep 17.

Zhang J, Dewar JM, Budzowska M, Motnenko A, Cohn MA, Walter JC. DNA interstrand cross-link repair requires replication-fork convergence. Nat Struct Mol Biol. 2015 Mar.

Duxin JP, Dewar JM, Yardimci H, Walter JC. Repair of a DNA-protein crosslink by replication-coupled proteolysis. Cell. 2014 Oct 9.

Castillo Bosch P, Segura-Bayona S, Koole W, van Heteren JT, Dewar JM, Tijsterman M, Knipscheer P. FANCJ promotes DNA synthesis through G-quadruplex structures. EMBO J. 2014 Nov 3.

Reviews and Book Chapters:

Dewar JM, Walter JC. Chromosome biology: conflict management for replication and transcription. Curr Biol. 2013 Mar 4.


Graduate work


Weile J, Pocock M, Cockell SJ, Lord P, Dewar JM, Holstein EM, Wilkinson D, Lydall D, Hallinan J, Wipat A. Customizable views on semantically integrated networks for systems biology. Bioinformatics. 2011 May 1.

Dewar JM, Lydall D. Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping. EMBO J. 2010 Dec 1.

Addinall SG, Downey M, Yu M, Zubko MK, Dewar J, Leake A, Hallinan J, Shaw O, James K, Wilkinson DJ, Wipat A, Durocher D, Lydall D. A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae. Genetics. 2008 Dec.

Reviews and Book Chapters:

Dewar JM, Lydall D. Simple, non-radioactive measurement of single-stranded DNA at telomeric, sub-telomeric, and genomic loci in budding yeast. Methods Mol Biol. 2012.

Dewar JM, Lydall D. Similarities and differences between “uncapped” telomeres and DNA double-strand breaks. Chromosoma. 2012 Apr.

Dewar JM, Lydall D. Telomere replication: Mre11 leads the way. Mol Cell. 2010 Jun 25.