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Yu Shyr

Director, Vanderbilt Center for Quantitative Sciences
Director, Vanderbilt Technologies for Advanced Genomics Analysis and Research Design (VANGARD)
Professor of Biostatistics, Biomedical Informatics and Health Policy


Yu Shyr, Ph.D., is the Chair of the Department of Biostatistics at Vanderbilt University School of Medicine. He is expert in biostatistical methodologies for clinical trial design, high-dimensional data preprocessing, and statistical or bioinformatics approaches to big data. He is on the advisory board of several Cancer Centers and SPOREs, and is Principal Investigator of a UO1 grant for the Barrett’s esophagus translational research network coordinating center (BETRNetCC), and PI for data coordination of the NCI SCLC Consortium. Dr. Shyr’s primary research interests are in developing statistical & bioinformatic methodology, specifically in experimental design for next-generation sequencing data, adaptive clinical trials, and nonparametric smoothing methods for longitudinal binary data, as well as in collaborative research in the fields of cancer biology, cancer epidemiology, and clinical trials. Department of BiostatisticsCenter for Quantitative Sciences.