Center for Cancer Systems Biology

Jonathan M. Irish, Ph.D., is Assistant Professor in the Department of Cell & Developmental Biology, and Pathology, Microbiology & Immunology at VUSM. He is Scientific Director of the Cancer & Immunology Core and the Mass Cytometry Center of Excellence. Research areas in Jonathan’s laboratory include neural stem cell and immune cell signaling interactions in brain tumors; machine learning algorithms to identify healthy and malignant cell types; and, immune mechanisms of disease and therapy response. The central goal of his research is a sytems-level understanding of changes at the single-cell level that alter signaling and lead to therapy-resistant populations in cancer and immunological diseases.