Publications

Tsyba N, Feng G, Grub LK, Held JP, Strozak AM, Burkewitz K, Patel MR. Tissue-specific heteroplasmy segregation is accompanied by a sharp mtDNA decline in C. elegans soma. iScience 26: 106349. 2023.

 

Donahue EKF, Ruark EM, Burkewitz K. Fundamental roles for inter-organelle communication in aging. Biochemical Society Transactions 50(5):1389-1402. 2022.

 

Held JP, Feng G, Saunders BR, Pereira CV, Burkewitz K, Patel MR. A tRNA processing enzyme is a key regulator of the mitochondrial unfolded protein response. Elife 11:e71634. 2022.

 

Burkewitz K*, Feng G, Dutta S, Kelley CA, Steinbaugh M, Cram EJ, Mair WB*. Atf-6 regulates lifespan through ER-mitochondrial calcium homeostasis. Cell Reports 32(10):108125. 2020.

*co-corresponding authors

 

Weir HJ, Yao P, Huynh FK, Escoubas CE, Goncalves R, Burkewitz K, Laboy R, Hirschey MD, Mair WB. Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and  Peroxisomal Remodeling. Cell Metabolism 26(6): 884-96. 2017.

 

Burkewitz K*, Weir HJ, Mair WB*. AMPK as a pro-longevity target, In: AMP-activated Protein Kinase, Cordero MD and Viollet B ed., Springer International Publishing, 227-256. 2016.

*co-corresponding authors

 

Jacobi D, Liu S, Burkewitz K, Kory N, Knudsen NH, Alexander RK, Unluturk U, Li X, Kang X, Hyde A, Gangl MR, Farese RV, Walther T, Mair WB, Lee CH. Hepatic Bmal1 regulates rhythmic mitochondrial dynamics and promotes metabolic fitness. Cell Metabolism 22(4): 709-720. 2015.

 

Burkewitz K, Morantte I, Weir HJ, Yeo R, Zhang Y, Huynh FK, Ilkayeva OR, Hirschey MD, Grant AR, Mair WB. Neuronal CRTC-1 governs systemic mitochondrial metabolism and lifespan via a catecholamine signal. Cell 160(5): 842-55. 2015.

 

Burkewitz K, Zhang Y, Mair WB. AMPK at the nexus of energetics and aging. Cell Metabolism 20(1): 10-25. 2014.

 

Reis-Rodrigues P, Kaul TK, Ho JH, Lucanic M, Burkewitz K, Mair WB, Held JM, Bohn LM, Gill MS. Synthetic ligands of cannabinoid receptors affect dauer formation in the nematode Caenorhabditis elegans. G3 (Bethesda) 6(6): 1695-705. 2016.

 

Burkewitz K, Choe KP, Choung-Hee Lee E, Deonarine A, Strange K. Characterization of the proteostasis roles of glycerol accumulation, protein degradation and protein synthesis during osmotic stress in C. elegans. PLoS ONE: e34153. PMC3314593. 2012.

 

Burkewitz K, Choe K, Strange K. Hypertonic stress induces rapid and widespread protein damage in C. elegans. Am J Physiol Cell Physiol 301(3): C566-576.  2011.

 

Flynt AS, Thatcher EJ, Burkewitz K, Li N, Liu Y, Patton JG. miR-8 microRNAs regulate the response to osmotic stress in zebrafish embryos.  J Cell Biol 185(1): 115-127. 2009.

 

Pedroso IM, Duarte LF, Yanez G, Burkewitz K, Fletcher TM. Sequence specificity of inter- and intramolecular G-quadruplex formation by human telomeric DNA. Biopolymers 87(1): 74-84. 2007.