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Publications

2024

BrownBreann L, Heterologous Expression and Purification of Eukaryotic ALA Synthase from E. coliIron Metabolism. Methods in Molecular Biology. 2024 2839
    TaylorJessica L, Ayres-GalhardoPedro H, BrownBreann L, Elucidating the role of human ALAS2 C-terminal mutations resulting in loss-of-function and diseaseBiochemistry. 2024 63 (13). 1636–1646

    2023

    2022

    TranU, BrownL, Structural Basis for Allostery in PLP-dependent EnzymesFrontiers in Molecular Biosciences. 2022 9:884281

    2021

    BrownBL, IversonTM, Handling heme with careNature Chemical Biology. 2021 17 751-752

      2020

      HungLY, TanakaY, HerbineK, PastoreC, SinghB, FergusonA, VoraN, DouglasB, ZulloK, BehrensEM, TanTLH, KohanskiMA, BryceP, LinC, KambayashiT, ReedDR, BrownBL, CohenNA, HerbertDR, Cellular context of IL-33 expression dictates impact on anti-helminth immunityScience Immunology. 2020 5 (53). eabc6259

        2019

        BrownBL, VieuxEF, KalastavadiT, KimS, ChenJZ, BakerTA, N domain of the Lon AAA+ protease controls assembly and substrate choiceProtein science : a publication of the Protein Society. 2019 Nov 21 28 (7). 1239-1251

        2018

        BrownBL, KardonJR, SauerRT, BakerTA, Structure of the Mitochondrial Aminolevulinic Acid Synthase, a Key Heme Biosynthetic EnzymeStructure (London, England : 1993). 2018 Mar 15 26 (4). 580-589.e4

        2013

        DavisJR, BrownBL, PageR, SelloJK, Study of PcaV from Streptomyces coelicolor yields new insights into ligand-responsive MarR family transcription factorsNucleic acids research. 2013 Feb 8 41 (6). 3888-900

        2012

        BrownBL, LordDM, GrigoriuS, PetiW, PageR, The Escherichia coli toxin MqsR destabilizes the transcriptional repression complex formed between the antitoxin MqsA and the mqsRA operon promoterThe Journal of biological chemistry. 2012 Nov 21 288 (2). 1286-94

        2011

        WangX, KimY, HongSH, MaQ, BrownBL, PuM, TaroneAM, BenedikMJ, PetiW, PageR, WoodTK, Antitoxin MqsA helps mediate the bacterial general stress responseNature chemical biology. 2011 Apr 24 7 (6). 359-66

        2010

        BrownBL, PageR, Preliminary crystallographic analysis of the Escherichia coli antitoxin MqsA (YgiT/b3021) in complex with mqsRA promoter DNAActa crystallographica. Section F, Structural biology and crystallization communications. 2010 Aug 26 66 (Pt 9). 1060-3

        2009

        BrownBL, GrigoriuS, KimY, ArrudaJM, DavenportA, WoodTK, PetiW, PageR, Three dimensional structure of the MqsR:MqsA complex: a novel TA pair comprised of a toxin homologous to RelE and an antitoxin with unique propertiesPLoS pathogens. 2009 Dec 24 5 (12). e1000706

        2008

        Full Publications List – Breann Brown