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Artwork credit: Christina Davies

The Brown Lab is interested in understanding how aberrations in macromolecular protein assembly underlie human diseases.

Our primary focus is using structural biology to understand the shape and nature of individual protein components, or “puzzle pieces.”

With this knowledge we can begin to understand how the pieces 1) fit together to maintain proper cell signaling and 2) how changes in protein structure lead to an inability to solve the “puzzle” and maintain human health.