Author
LassoHTP/LassoPred for Lasso Peptide Structure Prediction and Modeling
Sep. 20, 2025—Lasso peptides (LaPs) are RiPPs with a characteristic slipknot (lariat-knot) topology that confers exceptional thermal stability, protease resistance, and often potent bioactivity. Despite thousands of LaP sequences identified by bioinformatics, only ~50 have experimentally determined structures, largely because their irregular scaffold and isopeptide bond confound general-purpose predictors. LassoPred/LassoHTP enables end-to-end prediction and modeling of LaPs...
Congratulations to Matthew Tremblay for receiving Donald E. Pearson Outstanding Senior Award
May. 8, 2022—“Shows the most promise for an outstanding career”
Congratulations to Chris Jurich for being selected to receive V-ICB training grant!
May. 8, 2022—“Automating the computational tools for enzyme design”
The Alliance for Diversity in Science and Engineering @ Vanderbilt Chapter
Jan. 24, 2021—Follow our twitter account @AdseVu!
Information Extraction and Database Construction
Jan. 24, 2021—The Yang lab is building an integrated enzymology data ecosystem that makes the “dark matter” of enzyme kinetics accessible for predictive modeling and method development. IntEnzyDB provides a fast, flattened relational architecture that unifies enzyme structure and function across six EC classes and exposes a public web interface for streamlined access; using 1,050 structure-kinetics pairs,...
Welcome our virtual undergraduate researcher Qianzhen Shao
Jan. 24, 2021—Qianzhen Shao is an undergraduate student from Nankai University.
Welcome our graduate rotation student Reecan Juarez
Jan. 24, 2021—Reecan Juarez is a graduate student from Quantitative & Chemical Biology program at VUMC.
Welcome our undergraduate researcher Matthew Tremblay!
Jan. 24, 2021—Matthew Tremblay is a chemistry-computer science double major undergraduate student at Vanderbilt.
Welcome our research assistant Sarah Torrence
Jan. 24, 2021—Sarah is a master student from Vanderbilt Data Science Institute.
Welcome our research assistant Li Yuan!
Jan. 24, 2021—Li Yuan is a master student from Vanderbilt Data Science Institute.