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YOUNG LAB / VANDERBILT UNIVERSITY

Trace life.
Decode
metabolism.

We follow nutrients through biological systems to understand
disease and discover new opportunities in biotechnology.

CHEMICAL & BIOMOLECULAR ENGINEERING
NASHVILLE, TENNESSEE

Exploring central carbon metabolism

Move your cursor across the pathways, or select one above.
Simplified schematic; motion does not represent measured flux.

Stable isotope tracing
Metabolomics
Metabolic flux analysis

CONNECTED BY METABOLISM

Research Areas

From metabolism in the body to cells that manufacture useful
products, we investigate how nutrients are used—and what
changes their fate.

01 / METABOLIC HEALTH
Diabetes & Obesity

Understanding nutrient metabolism across cells,
tissues, and organs.


Metabolic tracers help us examine nutrient flow within
and between organs. Complementary cell-based studies
investigate mechanisms of metabolic dysfunction.


Explore the research ↗


02 / BIOPHARMACEUTICAL PRODUCTION

Cell Culture Engineering

Investigating cellular metabolism to improve
antibody production.


We study mitochondrial metabolism and metabolic
engineering in CHO cells, connecting nutrient use
and culture conditions with growth and productivity.


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03 / PHOTOSYNTHETIC SYSTEMS


Photosynthesis & Bioproducts


Following carbon from photosynthesis to useful products.


Carbon-13 flux analysis reveals responses to genetic
and environmental changes. Engineering studies explore
ways to direct carbon toward fuels, nutrients,
and chemicals.


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04 / CELL-DERIVED PRODUCTS

Extracellular Vesicle Biomanufacturing


Developing scalable approaches to stem-cell-derived
vesicle production.


We investigate stem-cell growth conditions and
scalable biomanufacturing strategies for producing
extracellular vesicles.


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EXPLORE THE EVIDENCE

Selected publications


Lab publication listing ↗

Young Lab group outside a Vanderbilt building
Curiosity connects us.

SCIENCE IS A SHARED PURSUIT

Different perspectives.
A shared curiosity.

Get to know the researchers and students behind the
Young Lab’s work, and explore the community that
makes it possible.


Lab members & alumni ↗

LET’S ASK THE NEXT QUESTION

Connect with the Young Lab.

Interested in our research, a potential collaboration,
or learning more about the lab? Start a conversation with us.


Contact the lab