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Tyska Lab

Tyska Lab Publications

2017

Feng Q , Bonder EM , Engevik AC , Zhang L , Tyska MJ , Goldenring JR , Gao N , Disruption of Rab8a and Rab11a causes formation of basolateral microvilli in neonatal enteropathy. Journal of cell science. 2017 Jun 8;
McKinley ET , Sui Y , Al-Kofahi Y , Millis BA , Tyska MJ , Roland JT , Santamaria-Pang A , Ohland CL , Jobin C , Franklin JL , Lau KS , Gerdes MJ , Coffey RJ , Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity. JCI insight. 2017 Jun 2; 2 (11).
Tonucci FM , Ferretti A , Almada E , Cribb P , Vena R , Hidalgo F , Favre C , Tyska MJ , Kaverina I , Larocca MC , Microtubules Regulate Brush Border Formation. Journal of cellular physiology. 2017 May 26;
Millis BA , Tyska MJ , High-Resolution Image Stitching as a Tool to Assess Tissue-Level Protein Distribution and Localization. Methods in molecular biology (Clifton, N.J.). 2017 ; 1606 281-296
Li J , He Y , Weck ML , Lu Q , Tyska MJ , Zhang M , Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins. Proceedings of the National Academy of Sciences of the United States of America. 2017 May 9; 114 (19). E3776-E3785
Weck ML , Grega-Larson NE , Tyska MJ , MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions. Current opinion in cell biology. 2017 Feb ; 44 68-78

2016

Taneja N , Fenix AM , Rathbun L , Millis BA , Tyska MJ , Hehnly H , Burnette DT , Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. Scientific reports. 2016 ; 6 29846
Sinha S , Hoshino D , Hong NH , Kirkbride KC , Grega-Larson NE , Seiki M , Tyska MJ , Weaver AM , Cortactin promotes exosome secretion by controlling branched actin dynamics. The Journal of cell biology. 2016 Jul 18; 214 (2). 197-213
Crawley SW , Weck ML , Grega-Larson NE , Shifrin DA , Tyska MJ , ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation. Developmental cell. 2016 Jan 25; 36 (2). 190-200
Tyska MJ , Listen to your gut: using adhesion to shape the surface of functionally diverse epithelia Rare Diseases. 2016 Jul 29;
Weck ML , Crawley SW , Stone CR , Tyska MJ , Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex. Current biology : CB. 2016 Oct 24; 26 (20). 2717-2728
Sommese RF , Hariadi RF , Kim K , Liu M , Tyska MJ , Sivaramakrishnan S , Patterning protein complexes on DNA nanostructures using a GFP nanobody. Protein science : a publication of the Protein Society. 2016 Nov ; 25 (11). 2089-2094
Raval MH , Quintero OA , Weck ML , Unrath WC , Gallagher JW , Cui R , Kachar B , Tyska MJ , Yengo CM , Impact of the motor and tail domains of class III myosins on regulating the formation and elongation of actin protrusions. The Journal of biological chemistry. 2016 Aug 31;
Grega-Larson NE , Crawley SW , Tyska MJ , Impact of cordon-bleu expression on actin cytoskeleton architecture and dynamics. Cytoskeleton (Hoboken, N.J.). 2016 Jul 28;
Tyska MJ , Brush Border Destruction by Enterohemorrhagic Escherichia coli (EHEC): New Insights From Organoid Culture. Cellular and molecular gastroenterology and hepatology. 2016 Jan ; 2 (1). 7-8

2015

Grega-Larson NE , Crawley SW , Erwin AL , Tyska MJ , Cordon bleu promotes the assembly of brush border microvilli. Molecular biology of the cell. 2015 Sep 9;

2014

Shifrin DA , Crawley SW , Grega-Larson NE , Tyska MJ , Dynamics of brush border remodeling induced by enteropathogenic E. coli. Gut Microbes. 2014 Jul 21; (In press).
Gérard A , Patino-Lopez G , Beemiller P , Nambiar R , Ben-Aissa K , Liu Y , Totah FJ , Tyska MJ , Shaw S , Krummel MF , Detection of Rare Antigen-Presenting Cells through T Cell-Intrinsic Meandering Motility, Mediated by Myo1g. Cell. 2014 Jul 31; 158 (3). 492-505
Shifrin DA , Crawley SW , Grega-Larson NE , Tyska MJ , Dynamics of brush border remodeling induced by enteropathogenic E. coli. Gut microbes. 2014 Jul 30; 5 (4).
Crawley SW , Mooseker MS , Tyska MJ , Shaping the intestinal brush border. The Journal of cell biology. 2014 Nov 24; 207 (4). 441-451
Shifrin AE , Crawley W , Grega-Larson E , Tyska J , Dynamics of brush border remodeling induced by enteropathogenic E. coli. Gut Microbes. 2014 ; (In press).
Mazerik JN , Kraft LJ , Kenworthy AK , Tyska MJ , Motor and tail homology 1 (Th1) domains antagonistically control myosin-1 dynamics. Biophysical journal. 2014 Feb 4; 106 (3). 649-58
Knowles BC , Tyska MJ , Goldenring JR , Apical vesicle trafficking takes center stage in neonatal enteropathies. Gastroenterology. 2014 Jul ; 147 (1). 15-7
Knowles BC , Roland JT , Krishnan M , Tyska MJ , Lapierre LA , Dickman PS , Goldenring JR , Shub MD , Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease. The Journal of clinical investigation. 2014 Jul 1; 124 (7). 2947-62
Crawley SW , Shifrin DA , Grega-Larson NE , McConnell RE , Benesh AE , Mao S , Zheng Y , Zheng QY , Nam KT , Millis BA , Kachar B , Tyska MJ , Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion. Cell. 2014 Apr 10; 157 (2). 433-46

2013

Hoshino D , Kirkbride KC , Costello K , Clark ES , Sinha S , Grega-Larson N , Tyska MJ , Weaver AM , Exosome secretion is enhanced by invadopodia and drives invasive behavior. Cell reports. 2013 Dec 12; 5 (5). 1159-68
Shifrin DA , Demory Beckler M , Coffey RJ , Tyska MJ , Extracellular vesicles: communication, coercion, and conditioning. Molecular biology of the cell. 2013 May ; 24 (9). 1253-9

2012

Shifrin DA , McConnell RE , Nambiar R , Higginbotham JN , Coffey RJ , Tyska MJ , Enterocyte microvillus-derived vesicles detoxify bacterial products and regulate epithelial-microbial interactions. Current biology : CB. 2012 Apr 10; 22 (7). 627-31
Mazerik JN , Tyska MJ , Myosin-1A targets to microvilli using multiple membrane binding motifs in the tail homology 1 (TH1) domain. The Journal of biological chemistry. 2012 Apr 13; 287 (16). 13104-15
Benesh AE , Fleming JT , Chiang C , Carter BD , Tyska MJ , Expression and localization of myosin-1d in the developing nervous system. Brain research. 2012 Feb 27; 1440 9-22
Shifrin DA , Tyska MJ , Ready…aim…fire into the lumen: a new role for enterocyte microvilli in gut host defense. Gut microbes. 2012 ; 3 (5). 460-2
Liu Y , Belkina NV , Park C , Nambiar R , Loughhead SM , Patino-Lopez G , Ben-Aissa K , Hao JJ , Kruhlak MJ , Qi H , von Andrian UH , Kehrl JH , Tyska MJ , Shaw S , Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice. Blood. 2012 Jan 12; 119 (2). 445-53
Pyrpassopoulos S , Feeser EA , Mazerik JN , Tyska MJ , Ostap EM , Membrane-bound myo1c powers asymmetric motility of actin filaments. Current biology : CB. 2012 Sep 25; 22 (18). 1688-92

2011

Pyburn TM , Bensing BA , Xiong YQ , Melancon BJ , Tomasiak TM , Ward NJ , Yankovskaya V , Oliver KM , Cecchini G , Sulikowski GA , Tyska MJ , Sullam PM , Iverson TM , A structural model for binding of the serine-rich repeat adhesin GspB to host carbohydrate receptors. PLoS pathogens. 2011 Jul ; 7 (7). e1002112
McConnell RE , Benesh AE , Mao S , Tabb DL , Tyska MJ , Proteomic analysis of the enterocyte brush border. American journal of physiology. Gastrointestinal and liver physiology. 2011 May ; 300 (5). G914-26
Higginbotham JN , Demory Beckler M , Gephart JD , Franklin JL , Bogatcheva G , Kremers GJ , Piston DW , Ayers GD , McConnell RE , Tyska MJ , Coffey RJ , Amphiregulin exosomes increase cancer cell invasion. Current biology : CB. 2011 May 10; 21 (9). 779-86

2010

McConnell RE , Tyska MJ , Leveraging the membrane – cytoskeleton interface with myosin-1. Trends in cell biology. 2010 Jul ; 20 (7). 418-26
Nambiar R , McConnell RE , Tyska MJ , Myosin motor function: the ins and outs of actin-based membrane protrusions. Cellular and molecular life sciences : CMLS. 2010 Apr ; 67 (8). 1239-54
Tyska MJ , Nambiar R , Myosin-1a: A motor for microvillar membrane movement and mechanics. Communicative & integrative biology. 2010 Jan ; 3 (1). 64-6
Benesh AE , Nambiar R , McConnell RE , Mao S , Tabb DL , Tyska MJ , Differential localization and dynamics of class I myosins in the enterocyte microvillus. Molecular biology of the cell. 2010 Mar 15; 21 (6). 970-8

2009

Nambiar R , McConnell RE , Tyska MJ , Control of cell membrane tension by myosin-I. Proceedings of the National Academy of Sciences of the United States of America. 2009 Jul 21; 106 (29). 11972-7
McConnell RE , Higginbotham JN , Shifrin DA , Tabb DL , Coffey RJ , Tyska MJ , The enterocyte microvillus is a vesicle-generating organelle. The Journal of cell biology. 2009 Jun 29; 185 (7). 1285-98
Wang J , Qin R , Ma Y , Wu H , Peters H , Tyska M , Shaheen NJ , Chen X , Differential gene expression in normal esophagus and Barrett’s esophagus. Journal of gastroenterology. 2009 ; 44 (9). 897-911

2008

Yengo CM , Ananthanarayanan SK , Brosey CA , Mao S , Tyska MJ , Human deafness mutation E385D disrupts the mechanochemical coupling and subcellular targeting of myosin-1a. Biophysical journal. 2008 Jan 15; 94 (2). L5-7

2007

McConnell RE , Tyska MJ , Myosin-1a powers the sliding of apical membrane along microvillar actin bundles. The Journal of cell biology. 2007 May 21; 177 (4). 671-81
O'Connell CB , Tyska MJ , Mooseker MS , Myosin at work: motor adaptations for a variety of cellular functions. Biochimica et biophysica acta. 2007 May ; 1773 (5). 615-30

2005

Tyska MJ , Mackey AT , Huang JD , Copeland NG , Jenkins NA , Mooseker MS , Myosin-1a is critical for normal brush border structure and composition. Molecular biology of the cell. 2005 May ; 16 (5). 2443-57

2004

Tyska MJ , Mooseker MS , A role for myosin-1A in the localization of a brush border disaccharidase. The Journal of cell biology. 2004 May 10; 165 (3). 395-405

2003

Tyska MJ , Mooseker MS , Myosin-V motility: these levers were made for walking. Trends in cell biology. 2003 Sep ; 13 (9). 447-51

2002

Tyska MJ , Mooseker MS , MYO1A (brush border myosin I) dynamics in the brush border of LLC-PK1-CL4 cells. Biophysical journal. 2002 Apr ; 82 (4). 1869-83
Tyska MJ , Warshaw DM , The myosin power stroke. Cell motility and the cytoskeleton. 2002 Jan ; 51 (1). 1-15
Post PL , Tyska MJ , O'Connell CB , Johung K , Hayward A , Mooseker MS , Myosin-IXb is a single-headed and processive motor. The Journal of biological chemistry. 2002 Apr 5; 277 (14). 11679-83

2001

Reck-Peterson SL , Tyska MJ , Novick PJ , Mooseker MS , The yeast class V myosins, Myo2p and Myo4p, are nonprocessive actin-based motors. The Journal of cell biology. 2001 May 28; 153 (5). 1121-6

2000

Palmiter KA , Tyska MJ , Haeberle JR , Alpert NR , Fananapazir L , Warshaw DM , R403Q and L908V mutant beta-cardiac myosin from patients with familial hypertrophic cardiomyopathy exhibit enhanced mechanical performance at the single molecule level. Journal of muscle research and cell motility. 2000 ; 21 (7). 609-20
Warshaw DM , Guilford WH , Freyzon Y , Krementsova E , Palmiter KA , Tyska MJ , Baker JE , Trybus KM , The light chain binding domain of expressed smooth muscle heavy meromyosin acts as a mechanical lever. The Journal of biological chemistry. 2000 Nov 24; 275 (47). 37167-72
Yamashita H , Tyska MJ , Warshaw DM , Lowey S , Trybus KM , Functional consequences of mutations in the smooth muscle myosin heavy chain at sites implicated in familial hypertrophic cardiomyopathy. The Journal of biological chemistry. 2000 Sep 8; 275 (36). 28045-52
Tyska MJ , Hayes E , Giewat M , Seidman CE , Seidman JG , Warshaw DM , Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy. Circulation research. 2000 Apr 14; 86 (7). 737-44

1999

Palmiter KA , Tyska MJ , Dupuis DE , Alpert NR , Warshaw DM , Kinetic differences at the single molecule level account for the functional diversity of rabbit cardiac myosin isoforms. The Journal of physiology. 1999 Sep 15; 519 Pt 3 669-78
Tyska MJ , Dupuis DE , Guilford WH , Patlak JB , Waller GS , Trybus KM , Warshaw DM , Lowey S , Two heads of myosin are better than one for generating force and motion. Proceedings of the National Academy of Sciences of the United States of America. 1999 Apr 13; 96 (8). 4402-7

1998

Lauzon AM , Tyska MJ , Rovner AS , Freyzon Y , Warshaw DM , Trybus KM , A 7-amino-acid insert in the heavy chain nucleotide binding loop alters the kinetics of smooth muscle myosin in the laser trap. Journal of muscle research and cell motility. 1998 Nov ; 19 (8). 825-37