{"id":93,"date":"2018-06-19T13:20:51","date_gmt":"2018-06-19T13:20:51","guid":{"rendered":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/welcome-to-the-obrien-lab\/"},"modified":"2026-06-19T03:48:58","modified_gmt":"2026-06-19T03:48:58","slug":"welcome-to-the-obrien-lab","status":"publish","type":"page","link":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/","title":{"rendered":"Welcome to the O&#8217;Brien Lab"},"content":{"rendered":"\n<h2>Info Text &#8211; Right Hand Column Placeholder<br \/>Refresh After Saving to Remove<\/h2>\n  <h3><strong>Contact Us<\/strong><\/h3>\n<p>The O&#8217;Brien Lab is located in room 8415 MRB IV<\/p>\n<p><strong>Lab Phone<\/strong><\/p>\n<p><a href=\"tel:(615) 936-1629\">(615) 936-1629<\/a><\/p>\n<p><strong>Office Phone <\/strong><\/p>\n<p><a href=\"tel:(615) 936-1503\">(615) 936-1503<\/a><\/p>\n<p><strong>Mailing Address<\/strong><\/p>\nDepartment of Molecular Physiology &amp; Biophysics<br \/>\n8415 MRB IV<br \/>\n2213 Garland Avenue<br \/>\nVanderbilt University School of Medicine<br \/>\nNashville, TN 37232-0615\n    <figure>\n        <img decoding=\"async\" src=\"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/wp-content\/uploads\/sites\/53\/2026\/06\/thumbnail_photobooth3.jpg\" alt=\" \" \/>\n            <figcaption>\n        Emily Overway and Darian Carroll, MP&amp;B student in the Gannon lab, celebrating passing their qualifying exam.\n      <\/figcaption>\n    <\/figure>\n        <p>The O&#8217;Brien Lab is interested in the metabolic function and transcriptional regulation of the glucose-6-phosphatase gene family and especially how these genes contribute to various diseases including diabetes. There are 3 members of this family designated G6PC, G6PC2 and G6PC3. These genes all play a role determining fasting blood glucose levels, a parameter that is correlated with the risk of cardiovascular-associated mortality and type 2 diabetes. But they are also associated with specific diseases namely glycogen storage disease type 1a (G6PC), type 2 diabetes (G6PC2) and neutropenia (G6PC3).<\/p>\n <!-- rich-text -->\n\n","protected":false},"excerpt":{"rendered":"<p>Info Text &#8211; Right Hand Column PlaceholderRefresh After Saving to Remove Contact Us The O&#8217;Brien Lab is located in room 8415 MRB IV Lab Phone (615) 936-1629 Office Phone (615) 936-1503 Mailing Address Department of Molecular Physiology &amp; Biophysics 8415 MRB IV 2213 Garland Avenue Vanderbilt University School of Medicine Nashville, TN 37232-0615 Emily Overway [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"class_list":["post-93","page","type-page","status-publish","hentry"],"acf":[],"ACF":{"topper_style":"default","topper_overline":"","topper_title":"Richard O'Brien Laboratory ","topper_intro":"","default_topper_background_type":"none","footer_style":"standard","recirculation_style":"none","nav_menu":"","nav_menu_secondary":"no","page_style_option":"details","page_theme_option":"light","page_class_name":"","page_jumplinks_option":"no"},"_links":{"self":[{"href":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/wp-json\/wp\/v2\/pages\/93","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/wp-json\/wp\/v2\/comments?post=93"}],"version-history":[{"count":9,"href":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/wp-json\/wp\/v2\/pages\/93\/revisions"}],"predecessor-version":[{"id":476,"href":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/wp-json\/wp\/v2\/pages\/93\/revisions\/476"}],"wp:attachment":[{"href":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/wp-json\/wp\/v2\/media?parent=93"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/richard-obrien-lab\/wp-json\/wp\/v2\/tags?post=93"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}