A new paper in Developmental Cell!
James O’Connor et al has published a new paper in Developmental Cell. The highlights of this paper include:
- Wounds induce a rapid increase in cytosolic calcium in cells around the wound
- The GPCR Mthl10 and its cytokine ligands Gbp1 and Gbp2 are required for this process
- Wound-induced proteases initiate the process by activating the cytokine proligands
- Computational modeling validates these steps as a mechanism for rapid wound detection
Congrats to everyone involved!
