Skip to main content

Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: potential role in liver fibrosis.


Amara| Lopez| Banan| Brown| Whalen| Myles| Ivy| Johnson| Schey| Tiriveedhi S| K| B| SK| M| E| MT| T| KL| VSuneetha| Karina| Babak| Sade-Kemi| Margaret| Elbert| Michael T| Terrance| Kevin L| Venkataswarup . Molecular immunology. 2015 3 ; 64(1). 26-35


The pro-inflammatory cytokines, tumor necrosis factor (TNF)-α, and interleukin (IL)-17, have been implicated in the pathogenesis of liver fibrosis. In this study, we investigated the role of TNFα and IL-17 toward induction of profibrotic factor, periostin.

Leave a Response