{"id":12,"date":"2023-04-18T12:47:49","date_gmt":"2023-04-18T17:47:49","guid":{"rendered":"https:\/\/lab.prd.vanderbilt.edu\/mml\/?page_id=12"},"modified":"2025-08-29T14:24:52","modified_gmt":"2025-08-29T19:24:52","slug":"publications","status":"publish","type":"page","link":"https:\/\/lab.vanderbilt.edu\/mml\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>For complete publications list, visit Dr. Merryman&#8217;s NCBI Bibliography as well as his Google Scholar site.<\/p>\n<ul>\n<li><strong>NCBI:\u00a0<\/strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/william.merryman.1\/bibliography\/public\/\">https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/william.merryman.1\/bibliography\/public\/<\/a><\/li>\n<li><strong>Google Scholar:<\/strong> <a href=\"https:\/\/scholar.google.com\/citations?user=VJW4LK4AAAAJ&amp;hl=en\">https:\/\/scholar.google.com\/citations?user=VJW4LK4AAAAJ&amp;hl=en<\/a><\/li>\n<\/ul>\n<h1>Select Publications<\/h1>\n<p><strong>Development of a Peripherally Restricted 5-HT<sub>2B<\/sub>\u00a0Partial Agonist for Treatment of Pulmonary Arterial Hypertension.<\/strong> Valentine MS, Bender AM, Shay S, Paffenroth KC, Gladson S, Dickerson JW, Watson KJ, Kapolka NJ, Boutaud O, Rook JM, Blackwell TS, Roth BL, Austin ED, West JD, Lindsley CW, Merryman WD.\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.jacbts.2023.06.014\">https:\/\/doi.org\/10.1016\/j.jacbts.2023.06.014<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Myocardial Neprilysin is Increased in Hypertrophic Cardiomyopathy.<\/strong> Armstrong DWJ, Riley LA, Su YR, Shah AS, Absi T, Gupta DK, Wells QS, Brinkley DM, Stevenson LW, Merryman WD.\u00a0<a href=\"https:\/\/doi.org\/10.1161\/circulationaha.123.064153\">https:\/\/doi.org\/10.1161\/circulationaha.123.064153<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Impaired macrophage trafficking and increased helper T-cell recruitment with loss of cadherin-11 in atherosclerotic immune response.<\/strong> Johnson CL, Riley L, Bersi M, Linton MF, Merryman WD.\u00a0<a href=\"https:\/\/doi.org\/10.1152\/ajpheart.00263.2021\">https:\/\/doi.org\/10.1152\/ajpheart.00263.2021<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Unloading the Stenotic Path to Identifying Medical Therapy for Calcific Aortic Valve Disease: Barriers and Opportunities.<\/strong> Lindman Br, Merryman WD.\u00a0<a href=\"https:\/\/doi.org\/10.1161\/circulationaha.120.052531\">https:\/\/doi.org\/10.1161\/circulationaha.120.052531<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>2B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery.<\/strong> Aaron M Bender, Lauren C Parr, William B Livingston, Craig W Lindsley, W David Merryman.\u00a0<a href=\"https:\/\/doi.org\/10.1021\/acs.jmedchem.3c01178\">https:\/\/doi.org\/10.1021\/acs.jmedchem.3c01178<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Targeting\u00a05-HT<sub>2B<\/sub>\u00a0Receptor Signaling Prevents Border Zone Expansion and Improves Microstructural Remodeling After Myocardial Infarction.<\/strong> J Caleb Snyder, Lance A Riley, Noah T Mallory, Matthew R Bersi, Prachi Umbarkar, Rekha Gautam, Qinkun Zhang, Anita Mahadevan-Jansen, Antonis K. Hatzopoulos, Luc Maroteaux, Hind Lal, W David Merryman. Circulation. 2021.\u00a0<a href=\"https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.120.051517\">https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.120.051517<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarction.<\/strong> Alison K Schroer, Matthew R Bersi, Cynthia R Clark, Qinkun Zhang, Lehanna H Sanders, Antonis K Hatzopoulos, Thomas L Force, Susan M Majka, Hind Lal, W David Merryman. Journal of Clinical Investigation Insight. 2019.\u00a0<a href=\"https:\/\/doi.org\/10.1172\/jci.insight.131545\">https:\/\/doi.org\/10.1172\/jci.insight.131545<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Bone Marrow-Derived Proangiogenic Cells Mediate Pulmonary Arteriole Stiffening via Serotonin 2B Receptor Dependent Mechanism.<\/strong> Nathaniel C Bloodworth, Cynthia R Clark, James D West, J Caleb Snider, Christa Gaskill, Sheila Shay, Christine Scott, Julie Bastarache, Santhi Gladson, Christy Moore, Reid D&#8217;Amico, Evan L Brittain, Harikrishna Tanjore, Timothy S Blackwell, Susan M Majka, W David Merryman. Circulation Research. 2018.\u00a0<a href=\"https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.313397\">https:\/\/doi.org\/10.1161\/CIRCRESAHA.118.313397<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Targeting Cadherin-11 Prevents Notch1-Mediated Calcific Aortic Valve Disease.<\/strong> Clark CR, Bowler MA, Snider JC, Merryman WD.\u00a0<a href=\"https:\/\/doi.org\/10.1161\/circulationaha.117.027771\">https:\/\/doi.org\/10.1161\/circulationaha.117.027771<\/a><\/p>\n<p>&nbsp;<\/p>\n<p><strong>The CNP\/NPR-B\/cGMP Axis is a Therapeutic Target in Calcific Aortic Stenosis.<\/strong> David WJ Armstrong, Deepak K Gupta, Brian R Lindman, W David Merryman. Journal of the American College of Cardiology: Basic to Translational Science. 2021.\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.jacbts.2021.09.009\">https:\/\/doi.org\/10.1016\/j.jacbts.2021.09.009<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>For complete publications list, visit Dr. Merryman&#8217;s NCBI Bibliography as well as his Google Scholar site. NCBI:\u00a0https:\/\/www.ncbi.nlm.nih.gov\/myncbi\/william.merryman.1\/bibliography\/public\/ Google Scholar: https:\/\/scholar.google.com\/citations?user=VJW4LK4AAAAJ&amp;hl=en Select Publications Development of a Peripherally Restricted 5-HT2B\u00a0Partial Agonist for Treatment of Pulmonary Arterial Hypertension. Valentine MS, Bender AM, Shay S, Paffenroth KC, Gladson S, Dickerson JW, Watson KJ, Kapolka NJ, Boutaud O, Rook JM,&#8230;<\/p>\n","protected":false},"author":453,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"class_list":["post-12","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/lab.vanderbilt.edu\/mml\/wp-json\/wp\/v2\/pages\/12","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lab.vanderbilt.edu\/mml\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lab.vanderbilt.edu\/mml\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/mml\/wp-json\/wp\/v2\/users\/453"}],"replies":[{"embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/mml\/wp-json\/wp\/v2\/comments?post=12"}],"version-history":[{"count":24,"href":"https:\/\/lab.vanderbilt.edu\/mml\/wp-json\/wp\/v2\/pages\/12\/revisions"}],"predecessor-version":[{"id":310,"href":"https:\/\/lab.vanderbilt.edu\/mml\/wp-json\/wp\/v2\/pages\/12\/revisions\/310"}],"wp:attachment":[{"href":"https:\/\/lab.vanderbilt.edu\/mml\/wp-json\/wp\/v2\/media?parent=12"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lab.vanderbilt.edu\/mml\/wp-json\/wp\/v2\/tags?post=12"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}